Recent advances in understanding the extracellular calcium-sensing receptor.
F1000Res
; 52016.
Article
em En
| MEDLINE
| ID: mdl-27803801
ABSTRACT
The extracellular calcium-sensing receptor (CaR), a ubiquitous class C G-protein-coupled receptor (GPCR), is responsible for the control of calcium homeostasis in body fluids. It integrates information about external Ca 2+ and a surfeit of other endogenous ligands into multiple intracellular signals, but how is this achieved? This review will focus on some of the exciting concepts in CaR signaling and pharmacology that have emerged in the last few years.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
F1000Res
Ano de publicação:
2016
Tipo de documento:
Article
País de afiliação:
Itália