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A multi-step peptidolytic cascade for amino acid recovery in chloroplasts.
Teixeira, Pedro F; Kmiec, Beata; Branca, Rui M M; Murcha, Monika W; Byzia, Anna; Ivanova, Aneta; Whelan, James; Drag, Marcin; Lehtiö, Janne; Glaser, Elzbieta.
Afiliação
  • Teixeira PF; Department of Biochemistry and Biophysics, Stockholm University, Arrhenius Laboratories for Natural Sciences, Stockholm, Sweden.
  • Kmiec B; Department of Biochemistry and Biophysics, Stockholm University, Arrhenius Laboratories for Natural Sciences, Stockholm, Sweden.
  • Branca RM; Clinical Proteomics Mass Spectrometry, Department of Oncology-Pathology, Science for Life Laboratory and Karolinska Institutet, Stockholm, Sweden.
  • Murcha MW; ARC Centre of Excellence in Plant Energy Biology, University of Western Australia, Crawley, Western Australia, Australia.
  • Byzia A; Division of Bioorganic Chemistry, Department of Chemistry, Wroclaw University of Technology, Wroclaw, Poland.
  • Ivanova A; ARC Centre of Excellence in Plant Energy Biology, University of Western Australia, Crawley, Western Australia, Australia.
  • Whelan J; ARC Centre of Excellence in Plant Energy Biology, Department of Animal, Plant and Soil Science, School of Life Science, La Trobe University, Victoria, Australia.
  • Drag M; Division of Bioorganic Chemistry, Department of Chemistry, Wroclaw University of Technology, Wroclaw, Poland.
  • Lehtiö J; Clinical Proteomics Mass Spectrometry, Department of Oncology-Pathology, Science for Life Laboratory and Karolinska Institutet, Stockholm, Sweden.
  • Glaser E; Department of Biochemistry and Biophysics, Stockholm University, Arrhenius Laboratories for Natural Sciences, Stockholm, Sweden.
Nat Chem Biol ; 13(1): 15-17, 2017 Jan.
Article em En | MEDLINE | ID: mdl-27820795
Plastids (including chloroplasts) are subcellular sites for a plethora of proteolytic reactions, required in functions ranging from protein biogenesis to quality control. Here we show that peptides generated from pre-protein maturation within chloroplasts of Arabidopsis thaliana are degraded to amino acids by a multi-step peptidolytic cascade consisting of oligopeptidases and aminopeptidases, effectively allowing the recovery of single amino acids within these organelles.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeo Hidrolases / Peptídeos / Cloroplastos / Arabidopsis / Proteólise / Aminoácidos Idioma: En Revista: Nat Chem Biol Assunto da revista: BIOLOGIA / QUIMICA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Suécia

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeo Hidrolases / Peptídeos / Cloroplastos / Arabidopsis / Proteólise / Aminoácidos Idioma: En Revista: Nat Chem Biol Assunto da revista: BIOLOGIA / QUIMICA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Suécia