Sex differences in neuroimmunity and pain.
J Neurosci Res
; 95(1-2): 500-508, 2017 01 02.
Article
em En
| MEDLINE
| ID: mdl-27870397
ABSTRACT
Differences in the prevalence of chronic pain in women vs. men are well known, and decades of laboratory experimentation have demonstrated that women are more sensitive to pain than are men. Attention has thus shifted to investigating mechanisms underlying such differences. Recent evidence suggests that neuroimmune modulation of pain may represent an important cause of sex differences. The current Review examines the evidence for gonadal hormone modulation of the immune system, immune system modulation of pain, and interactions that might help to explain sex differences in pain. © 2016 Wiley Periodicals, Inc.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Dor
/
Caracteres Sexuais
/
Encefalite
/
Sistema Imunitário
Tipo de estudo:
Risk_factors_studies
Limite:
Animals
/
Humans
Idioma:
En
Revista:
J Neurosci Res
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Canadá