Melanomas vs. nevi in high-risk patients under long-term monitoring with digital dermatoscopy: do melanomas and nevi already differ at baseline?
J Eur Acad Dermatol Venereol
; 31(6): 972-977, 2017 Jun.
Article
em En
| MEDLINE
| ID: mdl-27896853
ABSTRACT
BACKGROUND:
What lesions to select for a most efficient dermatoscopic monitoring of patients with multiple nevi remains an unresolved issue.OBJECTIVE:
To compare the grade of atypia of melanomas and nevi of the same patient at baseline.METHODS:
Prospective observational study using 236 dermatoscopic baseline images (59 quartets from 59 patients, each including one melanoma detected during follow-up and three nevi). Dermatologists (n = 26) were asked to assess the 'grade of dermatoscopic atypia' on a numerical scale and to identify the melanomas.RESULTS:
On average, each dermatologist identified 24 of 59 melanomas (40%, range 11-37). The number of correct picks was greater for dermatologists with moderate (mean 28) or high (mean 28) experience compared to beginners (mean 17; P < 0.001). In three of the 59 sets, none of the 26 dermatologists identified the melanoma. The mean grade of dermatoscopic atypia was 2.5 for nevi (95% CI 2.4-2.6) and 3.0 for melanomas (95% CI 2.9-3.1, P < 0.001).LIMITATIONS:
Rating dermatologists were informed that each quartet of images included one melanoma creating substantial deviation from a real-life situation.CONCLUSION:
A significant proportion of melanomas detected during follow-up cannot be differentiated from nevi at baseline. This necessitates the additional inclusion of less atypical lesions for monitoring.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Dermoscopia
/
Melanoma
/
Monitorização Fisiológica
/
Nevo
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
Limite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
J Eur Acad Dermatol Venereol
Assunto da revista:
DERMATOLOGIA
/
DOENCAS SEXUALMENTE TRANSMISSIVEIS
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Áustria