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Thumb Imprint Based Detection of Hyperbilirubinemia Using Luminescent Gold Nanoclusters.
Basu, Srestha; Sahoo, Amaresh Kumar; Paul, Anumita; Chattopadhyay, Arun.
Afiliação
  • Basu S; Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati 781039, India.
  • Sahoo AK; Centre for Nanotechnology, Indian Institute of Technology Guwahati, Guwahati 781039, India.
  • Paul A; Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati 781039, India.
  • Chattopadhyay A; Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati 781039, India.
Sci Rep ; 6: 39005, 2016 12 15.
Article em En | MEDLINE | ID: mdl-27976728
Early and easy detection of diseases, using point-of-care and inexpensive devices, not only provides option for early treatment but also reduces the risk of propagation. Herein we report the fabrication of a robust film based luminescence indicator of bilirubin, which can indicate hyperbilirubinemia through the thumb imprint of the patient. The UV-light induced luminescence intensity of the film, made out of chitosan stabilised gold (Au) nanoclusters, which was effectively quenched in the presence of Cu2+ ions, recovered in the presence of bilirubin from skin or blood serum. Moreover, the sensitivity of detection of bilirubin was tuneable with the amount of Cu2+ added, thereby facilitating the detection of the desired concentration range of bilirubin.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bilirrubina / Sistemas Automatizados de Assistência Junto ao Leito / Cobre / Dermatoglifia / Nanopartículas Metálicas / Ouro / Icterícia Tipo de estudo: Diagnostic_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: Sci Rep Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Índia

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bilirrubina / Sistemas Automatizados de Assistência Junto ao Leito / Cobre / Dermatoglifia / Nanopartículas Metálicas / Ouro / Icterícia Tipo de estudo: Diagnostic_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: Sci Rep Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Índia