Nocodazole treatment interrupted Brucella abortus invasion in RAW 264.7 cells, and successfully attenuated splenic proliferation with enhanced inflammatory response in mice.

Reyes, Alisha Wehdnesday Bernardo; Hop, Huynh Tan; Arayan, Lauren Togonon; Huy, Tran Xuan Ngoc; Min, Wongi; Lee, Hu Jang; Chang, Hong Hee; Kim, Suk

Reyes, Alisha Wehdnesday Bernardo; Hop, Huynh Tan; Arayan, Lauren Togonon; Huy, Tran Xuan Ngoc; Min, Wongi; Lee, Hu Jang; Chang, Hong Hee; Kim, Suk.

Afiliação

Reyes AW; Institute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University, Jinju, 660-701, Republic of Korea; Department of Veterinary Paraclinical Sciences, College of Veterinary Medicine, University of the Philippines, Los Baños College, Laguna, 4031, Philippines.
Hop HT; Institute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University, Jinju, 660-701, Republic of Korea.
Arayan LT; Institute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University, Jinju, 660-701, Republic of Korea.
Huy TX; Institute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University, Jinju, 660-701, Republic of Korea.
Min W; Institute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University, Jinju, 660-701, Republic of Korea.
Lee HJ; Institute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University, Jinju, 660-701, Republic of Korea.
Chang HH; Institute of Agriculture and Life Science, Gyeongsang National University, Jinju, 660-701, Republic of Korea.
Kim S; Institute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University, Jinju, 660-701, Republic of Korea; Institute of Agriculture and Life Science, Gyeongsang National University, Jinju, 660-701, Republic of Korea. Electronic address: kimsuk@gnu.ac.kr.

Microb Pathog ; 103: 87-93, 2017 Feb.

Article em En | MEDLINE | ID: mdl-28017899

Assuntos

Antibacterianos/farmacologia; Brucella abortus/efeitos dos fármacos; Brucelose/microbiologia; Nocodazol/farmacologia; Baço/microbiologia; Actinas/metabolismo; Animais; Aderência Bacteriana/efeitos dos fármacos; Carga Bacteriana; Brucella abortus/patogenicidade; Brucelose/tratamento farmacológico; Brucelose/imunologia; Brucelose/metabolismo; Sobrevivência Celular/efeitos dos fármacos; Modelos Animais de Doenças; Macrófagos/efeitos dos fármacos; Macrófagos/imunologia; Macrófagos/metabolismo; Macrófagos/microbiologia; Camundongos; Viabilidade Microbiana/efeitos dos fármacos; Proteínas Quinases Ativadas por Mitógeno/metabolismo; Fosforilação; Células RAW 264.7; Baço/imunologia; Baço/metabolismo; Baço/patologia

Palavras-chave

B. abortus; Cytokine; F-actin; MAPKs; Macrophages; Nocodazole

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Baço / Brucella abortus / Brucelose / Nocodazol / Antibacterianos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Microb Pathog Assunto da revista: DOENCAS TRANSMISSIVEIS / MICROBIOLOGIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Filipinas

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