The relationship between right-to-left shunt and brain white matter lesions in Japanese patients with migraine: a single center study.
J Headache Pain
; 18(1): 3, 2017 Dec.
Article
em En
| MEDLINE
| ID: mdl-28063107
ABSTRACT
BACKGROUND:
There may be a link between right-to-left shunt (RLs) and brain white matter lesions (WMLs) in patients with migraine. In this study, we assessed the relationship between WMLs and RLs in Japanese migraine patients.METHODS:
A total of 107 consecutive patients with migraine with (MA) and without aura (MWOA) were included in this study. Contrast transcranial Doppler ultrasound was used to detect RLs. WMLs were graded using brain magnetic resonance imaging based on well-established criteria.FINDINGS:
The prevalence of RLs was significantly increased in the WMLs positive group (n = 24) compared with the WMLs negative group (n = 83) (75.0% vs. 47.0%, p = 0.015). In prevalence of WMLs between MA and MWOA patients, there were no statistical differences (p = 0.410). Logistic regression analysis adjusted by age and disease duration of migraine identified an RLs-positive status as the sole determinant for the presence of WMLs (OR = 6.15; 95% CI 1.82-20.8; p = 0.003)CONCLUSION:
Our study suggests a possible link between RLs and WMLs in Japanese patients with migraine.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ultrassonografia Doppler Transcraniana
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Forame Oval Patente
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Substância Branca
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Transtornos de Enxaqueca
Tipo de estudo:
Prevalence_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Adult
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Female
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Humans
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Male
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Middle aged
País/Região como assunto:
Asia
Idioma:
En
Revista:
J Headache Pain
Assunto da revista:
MEDICINA INTERNA
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NEUROLOGIA
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PSICOFISIOLOGIA
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Japão