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Suppression of RUNX1/ETO oncogenic activity by a small molecule inhibitor of tetramerization.
Schanda, Julia; Lee, Chun-Wei; Wohlan, Katharina; Müller-Kuller, Uta; Kunkel, Hana; Coco, Isabell Quagliano-Lo; Stein, Stefan; Metz, Alexander; Koch, Joachim; Lausen, Jörn; Platzbecker, Uwe; Medyouf, Hind; Gohlke, Holger; Heuser, Michael; Eder, Matthias; Grez, Manuel; Scherr, Michaela; Wichmann, Christian.
Afiliação
  • Schanda J; Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt, Germany.
  • Lee CW; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Germany.
  • Wohlan K; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Germany.
  • Müller-Kuller U; Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt, Germany.
  • Kunkel H; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Coco IQ; Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt, Germany.
  • Stein S; Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt, Germany.
  • Metz A; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Koch J; Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt, Germany.
  • Lausen J; Institute for Pharmaceutical and Medicinal Chemistry, Department of Mathematics and Natural Sciences, Heinrich Heine University Düsseldorf, Germany.
  • Platzbecker U; Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt, Germany.
  • Medyouf H; Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt, Germany.
  • Gohlke H; Department of Hematology, Medical Clinic and Polyclinic I, University Hospital Carl Gustav Carus, Dresden, Germany.
  • Heuser M; Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt, Germany.
  • Eder M; Institute for Pharmaceutical and Medicinal Chemistry, Department of Mathematics and Natural Sciences, Heinrich Heine University Düsseldorf, Germany.
  • Grez M; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Germany.
  • Scherr M; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Germany.
  • Wichmann C; Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt, Germany grez@gsh.uni-frankfurt.de.
Haematologica ; 102(5): e170-e174, 2017 05.
Article em En | MEDLINE | ID: mdl-28154087
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Fusão Oncogênica / Subunidade alfa 2 de Fator de Ligação ao Core / Multimerização Proteica / Proteína 1 Parceira de Translocação de RUNX1 / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Haematologica Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Fusão Oncogênica / Subunidade alfa 2 de Fator de Ligação ao Core / Multimerização Proteica / Proteína 1 Parceira de Translocação de RUNX1 / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Haematologica Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Alemanha