One Cycle Fuels Another: The Energetics of Neurotransmitter Release.

Silm, Katlin; Edwards, Robert H

Silm, Katlin; Edwards, Robert H.

Afiliação

Silm K; Kavli Institute for Fundamental Neuroscience, UCSF Weill Institute for Neurosciences, University of California, San Francisco, 600 16th Street, GH-N272B, San Francisco, CA 94143, USA; Departments of Neurology and Physiology, UCSF School of Medicine, University of California, San Francisco, 600 16th Street, GH-N272B, San Francisco, CA 94143, USA.
Edwards RH; Kavli Institute for Fundamental Neuroscience, UCSF Weill Institute for Neurosciences, University of California, San Francisco, 600 16th Street, GH-N272B, San Francisco, CA 94143, USA; Departments of Neurology and Physiology, UCSF School of Medicine, University of California, San Francisco, 600 16th Street, GH-N272B, San Francisco, CA 94143, USA. Electronic address: robert.edwards@ucsf.edu.

Neuron ; 93(3): 470-472, 2017 Feb 08.

Article em En | MEDLINE | ID: mdl-28182901

ABSTRACT

ABSTRACT

In this issue of Neuron, Ashrafi et al. (2017) show that activity induces translocation of the insulin-regulated glucose transporter GLUT4 to the plasma membrane, where it sustains the ATP production required for synaptic vesicle cycling. However, translocation occurs from presynaptic membranes other than synaptic vesicles and involves a distinct molecular mechanism.

Assuntos

Transportador de Glucose Tipo 4; Insulina; Transporte Biológico; Membrana Celular; Proteínas Musculares; Neurotransmissores; Vesículas Sinápticas

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transportador de Glucose Tipo 4 / Insulina Idioma: En Revista: Neuron Assunto da revista: NEUROLOGIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos

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