Effect of Low-Intensity Cavitation on the Isolated Human Thoracic Artery In Vitro.
Ultrasound Med Biol
; 43(5): 1040-1047, 2017 05.
Article
em En
| MEDLINE
| ID: mdl-28196770
ABSTRACT
Reported here are the results of an experimental study on the response to low-intensity cavitation induced by low-frequency (4-6 W/cm2, 20 kHz and 32.6 kHz) ultrasound of isolated human arterial samples taken during conventional myocardial revascularization operations. Studies have found that low-frequency ultrasound results in a significant (48%-54%) increase in isometric contraction force and does not depend on the number of exposures (10 or 20) or the time passed since the start of ultrasound (0, 10 and 20 min), but does depend on the frequency and location (internal or external) of the blood vessels for the application of ultrasound. Diltiazem (an inhibitor of slow calcium channels) and carbachol (an agonist of muscarinic receptors) used in a concentration-dependent manner did not modify the relaxation dynamics of smooth muscle affected by ultrasound. Thus, ultrasound conditioned to the augmentation of the isometric contraction force the smooth muscle of blood vessels and did not improve endothelial- and calcium channel blocker-dependent relaxation.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Artérias Torácicas
/
Ondas Ultrassônicas
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Contração Isométrica
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Revascularização Miocárdica
Limite:
Aged
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Female
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Humans
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Male
Idioma:
En
Revista:
Ultrasound Med Biol
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Lituânia