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Association of Rare and Common Variation in the Lipoprotein Lipase Gene With Coronary Artery Disease.
Khera, Amit V; Won, Hong-Hee; Peloso, Gina M; O'Dushlaine, Colm; Liu, Dajiang; Stitziel, Nathan O; Natarajan, Pradeep; Nomura, Akihiro; Emdin, Connor A; Gupta, Namrata; Borecki, Ingrid B; Asselta, Rosanna; Duga, Stefano; Merlini, Piera Angelica; Correa, Adolfo; Kessler, Thorsten; Wilson, James G; Bown, Matthew J; Hall, Alistair S; Braund, Peter S; Carey, David J; Murray, Michael F; Kirchner, H Lester; Leader, Joseph B; Lavage, Daniel R; Manus, J Neil; Hartzel, Dustin N; Samani, Nilesh J; Schunkert, Heribert; Marrugat, Jaume; Elosua, Roberto; McPherson, Ruth; Farrall, Martin; Watkins, Hugh; Lander, Eric S; Rader, Daniel J; Danesh, John; Ardissino, Diego; Gabriel, Stacey; Willer, Cristen; Abecasis, Gonçalo R; Saleheen, Danish; Dewey, Frederick E; Kathiresan, Sekar.
Afiliação
  • Khera AV; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts2Center for Genomic Medicine, Massachusetts General Hospital, Harvard Medical School, Boston3Cardiology Division, Massachusetts General Hospital, Harvard Medical School, Boston.
  • Won HH; Samsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan University, Samsung Medical Center, Seoul, Republic of Korea.
  • Peloso GM; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts5Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts.
  • O'Dushlaine C; Regeneron Genetics Center, Tarrytown, New Jersey.
  • Liu D; Department of Public Health Sciences, Institute for Personalized Medicine, Penn State College of Medicine, Hershey, Pennsylvania.
  • Stitziel NO; Department of Medicine, Washington University School of Medicine, St Louis, Missouri9Department of Genetics, Washington University School of Medicine, St Louis, Missouri10McDonnell Genome Institute, Washington University School of Medicine, St Louis, Missouri.
  • Natarajan P; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts2Center for Genomic Medicine, Massachusetts General Hospital, Harvard Medical School, Boston3Cardiology Division, Massachusetts General Hospital, Harvard Medical School, Boston.
  • Nomura A; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts2Center for Genomic Medicine, Massachusetts General Hospital, Harvard Medical School, Boston3Cardiology Division, Massachusetts General Hospital, Harvard Medical School, Boston.
  • Emdin CA; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts2Center for Genomic Medicine, Massachusetts General Hospital, Harvard Medical School, Boston3Cardiology Division, Massachusetts General Hospital, Harvard Medical School, Boston.
  • Gupta N; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts.
  • Borecki IB; Regeneron Genetics Center, Tarrytown, New Jersey.
  • Asselta R; Department of Biomedical Sciences, Humanitas University, Milan, Italy12Humanitas Clinical and Research Center, Milan, Italy.
  • Duga S; Department of Biomedical Sciences, Humanitas University, Milan, Italy12Humanitas Clinical and Research Center, Milan, Italy.
  • Merlini PA; Ospedale Niguarda, Milano, Italy.
  • Correa A; Department of Medicine, University of Mississippi Medical Center, Jackson.
  • Kessler T; Munich Heart Alliance, München, Germany16Deutsches Herzzentrum München, Technische Universität München, Deutsches Zentrum für Herz-Kreislauf-Forschung, München, Germany.
  • Wilson JG; Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson.
  • Bown MJ; NIHR Leicester Cardiovascular Biomedical Research Unit, Department of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom.
  • Hall AS; Leeds Institute of Cardiovascular and Metabolic Medicine, Leeds University, Leeds, United Kingdom.
  • Braund PS; NIHR Leicester Cardiovascular Biomedical Research Unit, Department of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom.
  • Carey DJ; Geisinger Health System, Danville, Pennsylvania.
  • Murray MF; Geisinger Health System, Danville, Pennsylvania.
  • Kirchner HL; Geisinger Health System, Danville, Pennsylvania.
  • Leader JB; Geisinger Health System, Danville, Pennsylvania.
  • Lavage DR; Geisinger Health System, Danville, Pennsylvania.
  • Manus JN; Geisinger Health System, Danville, Pennsylvania.
  • Hartzel DN; Geisinger Health System, Danville, Pennsylvania.
  • Samani NJ; NIHR Leicester Cardiovascular Biomedical Research Unit, Department of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom.
  • Schunkert H; Deutsches Herzzentrum München, Technische Universität München, Deutsches Zentrum für Herz-Kreislauf-Forschung, München, Germany.
  • Marrugat J; Cardiovascular Epidemiology and Genetics, Hospital del Mar Research Institute, Barcelona, Spain.
  • Elosua R; Cardiovascular Epidemiology and Genetics, Hospital del Mar Research Institute, Barcelona, Spain.
  • McPherson R; University of Ottawa Heart Institute, Ottawa, Ontario, Canada.
  • Farrall M; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom24Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.
  • Watkins H; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom24Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.
  • Lander ES; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts.
  • Rader DJ; Department of Genetics, University of Pennsylvania, Philadelphia.
  • Danesh J; Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom27Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom28NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care
  • Ardissino D; Division of Cardiology, Azienda Ospedaliero-Universitaria di Parma, Parma, Italy31Associazione per lo Studio Della Trombosi in Cardiologia, Pavia, Italy.
  • Gabriel S; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts.
  • Willer C; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor33Department of Human Genetics, University of Michigan, Ann Arbor34Department of Internal Medicine, University of Michigan, Ann Arbor.
  • Abecasis GR; Center for Statistical Genetics, Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor.
  • Saleheen D; Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia.
  • Dewey FE; Regeneron Genetics Center, Tarrytown, New Jersey.
  • Kathiresan S; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts2Center for Genomic Medicine, Massachusetts General Hospital, Harvard Medical School, Boston3Cardiology Division, Massachusetts General Hospital, Harvard Medical School, Boston.
JAMA ; 317(9): 937-946, 2017 03 07.
Article em En | MEDLINE | ID: mdl-28267856
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença da Artéria Coronariana / Lipase Lipoproteica / Mutação Tipo de estudo: Etiology_studies / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: JAMA Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença da Artéria Coronariana / Lipase Lipoproteica / Mutação Tipo de estudo: Etiology_studies / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: JAMA Ano de publicação: 2017 Tipo de documento: Article