Changing the Therapeutic Landscape in Non-small Cell Lung Cancers: the Evolution of Comprehensive Molecular Profiling Improves Access to Therapy.

Sabari, Joshua K; Santini, Fernando; Bergagnini, Isabella; Lai, W Victoria; Arbour, Kathryn C; Drilon, Alexander

Sabari, Joshua K; Santini, Fernando; Bergagnini, Isabella; Lai, W Victoria; Arbour, Kathryn C; Drilon, Alexander.

Afiliação

Sabari JK; Thoracic Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, 300 East 66th Street, New York, NY, 10065, USA.
Santini F; Thoracic Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, 300 East 66th Street, New York, NY, 10065, USA.
Bergagnini I; Thoracic Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, 300 East 66th Street, New York, NY, 10065, USA.
Lai WV; Thoracic Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, 300 East 66th Street, New York, NY, 10065, USA.
Arbour KC; Thoracic Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, 300 East 66th Street, New York, NY, 10065, USA.
Drilon A; Thoracic Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, Weill Cornell Medical College, 300 East 66th Street, New York, NY, 10065, USA. drilona@mskcc.org.

Curr Oncol Rep ; 19(4): 24, 2017 Apr.

Article em En | MEDLINE | ID: mdl-28303491

Assuntos

Carcinoma Pulmonar de Células não Pequenas/tratamento farmacológico; Neoplasias Pulmonares/tratamento farmacológico; Biomarcadores Tumorais/genética; Carcinoma Pulmonar de Células não Pequenas/genética; Sequenciamento de Nucleotídeos em Larga Escala/métodos; Humanos; Neoplasias Pulmonares/genética; Terapia de Alvo Molecular/métodos; Medicina de Precisão/métodos

Palavras-chave

MET exon 14 skipping alteration; Molecular diagnostics; NTRK fusion; Next-generation sequencing (NGS); Non-small cell lung cancer (NSCLC); Precision medicine; RNA sequencing; Targeted therapy

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Neoplasias Pulmonares Limite: Humans Idioma: En Revista: Curr Oncol Rep Assunto da revista: NEOPLASIAS Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google