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Prediction of hepatotoxicity for drugs using human pluripotent stem cell-derived hepatocytes.
Kim, Jong Hyun; Wang, Min; Lee, Jaehun; Park, Han-Jin; Han, Chungseong; Hong, Hee Su; Kim, Jeong Seong; An, Geun Ho; Park, Kijung; Park, Hee-Kyung; Zhu, Shi Feng; Sun, Xiao-Bo; Kim, Jong-Hoon; Woo, Dong-Hun.
Afiliação
  • Kim JH; Laboratory of Stem Cells, NEXEL Co., Ltd., 9th floor, 21 Wangsan-ro, Dongdaemun-gu, Seoul, 02580, South Korea.
  • Wang M; Institute of Medicinal Plant Development (IMPLAD), Chinese Academy of Medical Sciences/Peking Union Medical College (CAMS/PUMC), No 151, North Road Malianwa, Haidian District, Beijing, 100093, China.
  • Lee J; Laboratory of Stem Cells and Tissue Regeneration, Department of Biotechnology, College of Life Sciences and Biotechnology, Science Campus, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul, 02841, South Korea.
  • Park HJ; Predictive Model Research Center, Korea Institute of Toxicology, Daejeon, 34114, South Korea.
  • Han C; Laboratory of Stem Cells, NEXEL Co., Ltd., 9th floor, 21 Wangsan-ro, Dongdaemun-gu, Seoul, 02580, South Korea.
  • Hong HS; Laboratory of Stem Cells, NEXEL Co., Ltd., 9th floor, 21 Wangsan-ro, Dongdaemun-gu, Seoul, 02580, South Korea.
  • Kim JS; Laboratory of Stem Cells, NEXEL Co., Ltd., 9th floor, 21 Wangsan-ro, Dongdaemun-gu, Seoul, 02580, South Korea.
  • An GH; Laboratory of Stem Cells, NEXEL Co., Ltd., 9th floor, 21 Wangsan-ro, Dongdaemun-gu, Seoul, 02580, South Korea.
  • Park K; Laboratory of Stem Cells, NEXEL Co., Ltd., 9th floor, 21 Wangsan-ro, Dongdaemun-gu, Seoul, 02580, South Korea.
  • Park HK; Department of Oral Medicine and Oral Diagnosis, School of Dentistry and Dental Research Institute, Seoul National University, Yunkeun-dong 28, Chongro-Ku, Seoul, 03080, South Korea.
  • Zhu SF; School of Continuing Education, Yanbian University, 977 Gongyuan Str, Yanji City, Jilin Province, 133002, China.
  • Sun XB; Institute of Medicinal Plant Development (IMPLAD), Chinese Academy of Medical Sciences/Peking Union Medical College (CAMS/PUMC), No 151, North Road Malianwa, Haidian District, Beijing, 100093, China. sun-xiaobo@163.com.
  • Kim JH; Laboratory of Stem Cells and Tissue Regeneration, Department of Biotechnology, College of Life Sciences and Biotechnology, Science Campus, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul, 02841, South Korea. jhkim@korea.ac.kr.
  • Woo DH; Laboratory of Stem Cells, NEXEL Co., Ltd., 9th floor, 21 Wangsan-ro, Dongdaemun-gu, Seoul, 02580, South Korea. dhwoo@nexel.co.kr.
Cell Biol Toxicol ; 34(1): 51-64, 2018 02.
Article em En | MEDLINE | ID: mdl-28382404
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hepatócitos / Células-Tronco Pluripotentes / Doença Hepática Induzida por Substâncias e Drogas / Fígado Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Cell Biol Toxicol Assunto da revista: TOXICOLOGIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Coréia do Sul
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hepatócitos / Células-Tronco Pluripotentes / Doença Hepática Induzida por Substâncias e Drogas / Fígado Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Cell Biol Toxicol Assunto da revista: TOXICOLOGIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Coréia do Sul