Brain tuberculoma, an unusual cause of stroke in a child with trisomy 21: a case report.
J Med Case Rep
; 11(1): 114, 2017 Apr 18.
Article
em En
| MEDLINE
| ID: mdl-28416000
ABSTRACT
BACKGROUND:
Tuberculosis remains a public health problem in developing countries and is associated with lethal central nervous system complications. Intracranial tuberculomas occur in 13% of children with neurotuberculosis. Patients with trisomy 21 have an increased risk for stroke, which usually stems from cardiovascular defects. CASE PRESENTATION We report a case of a 12-year-old Sudanese boy with trisomy 21 who was presented to our hospital with focal convulsions and right-sided weakness. The results of neuroimaging and histopathological examinations were consistent with cerebral tuberculoma. The patient had a good initial response to antituberculosis drugs and steroids. To the best of our knowledge, this is the first case report of multiple brain tuberculomas described in a child with trisomy 21.CONCLUSIONS:
Patients with trisomy 21 have an increased risk for stroke. Our patient had an exceptional case of stroke caused by tuberculoma. The present case emphasizes the need to consider tuberculomas in the differential diagnosis of children with neurological symptoms living in areas of high tuberculosis incidence.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Tuberculoma Intracraniano
/
Síndrome de Down
/
Acidente Vascular Cerebral
Tipo de estudo:
Diagnostic_studies
Limite:
Child
/
Humans
/
Male
País/Região como assunto:
Africa
Idioma:
En
Revista:
J Med Case Rep
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Sudão