Systemic and local anti-nociceptive effects of simvastatin in the rat formalin assay: Role of peroxisome proliferator-activated receptor Î³ and nitric oxide.

Mansouri, Mohammad Taghi; Naghizadeh, Bahareh; Ghorbanzadeh, Behnam; Alboghobeish, Soheila

Mansouri, Mohammad Taghi; Naghizadeh, Bahareh; Ghorbanzadeh, Behnam; Alboghobeish, Soheila.

Afiliação

Mansouri MT; Department of Pharmacology, School of Pharmacy, Physiology Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Naghizadeh B; Department of Pharmacology, School of Pharmacy, Pain Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Ghorbanzadeh B; Department of Pharmacology, School of Medicine, Dezful University of Medical Sciences, Dezful, Iran.
Alboghobeish S; Department of Pharmacology, School of Pharmacy, Physiology Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

J Neurosci Res ; 95(9): 1776-1785, 2017 09.

Article em En | MEDLINE | ID: mdl-28419516

Assuntos

Nociceptividade/efeitos dos fármacos; PPAR gama/metabolismo; Sinvastatina/farmacologia; Animais; Formaldeído/toxicidade; Inibidores de Hidroximetilglutaril-CoA Redutases/farmacologia; Irritantes/toxicidade; Masculino; Óxido Nítrico/metabolismo; Dor/induzido quimicamente; Ratos; Ratos Wistar

Palavras-chave

Antinociception; Formalin assay; Nitric oxide; PPARÎ³; Simvastatin

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sinvastatina / PPAR gama / Nociceptividade Limite: Animals Idioma: En Revista: J Neurosci Res Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Irã

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