Context-dependent intravital imaging of therapeutic response using intramolecular FRET biosensors.

Conway, James R W; Warren, Sean C; Timpson, Paul

Conway, James R W; Warren, Sean C; Timpson, Paul.

Afiliação

Conway JRW; Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Cancer Division, Sydney, NSW 2010, Australia; St Vincent's Clinical School, Faculty of Medicine, University of NSW, Sydney, NSW 2010, Australia.
Warren SC; Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Cancer Division, Sydney, NSW 2010, Australia; St Vincent's Clinical School, Faculty of Medicine, University of NSW, Sydney, NSW 2010, Australia.
Timpson P; Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Cancer Division, Sydney, NSW 2010, Australia; St Vincent's Clinical School, Faculty of Medicine, University of NSW, Sydney, NSW 2010, Australia. Electronic address: p.timpson@garvan.org.au.

Methods ; 128: 78-94, 2017 09 01.

Article em En | MEDLINE | ID: mdl-28435000

Assuntos

Técnicas Biossensoriais/métodos; Transferência Ressonante de Energia de Fluorescência/métodos; Microscopia Intravital/métodos; Animais; Humanos; Retalhos Cirúrgicos; Resultado do Tratamento; Ensaios Antitumorais Modelo de Xenoenxerto/métodos

Palavras-chave

Biosensors; Cancer microenvironment; Drug target validation; FLIM-FRET; Hypoxia; Intravital microscopy

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Técnicas Biossensoriais / Transferência Ressonante de Energia de Fluorescência / Microscopia Intravital Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Methods Assunto da revista: BIOQUIMICA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Austrália

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