A-to-I RNA editing of BLCAP lost the inhibition to STAT3 activation in cervical cancer.

Chen, Wen; He, Wenrong; Cai, Hongbing; Hu, Bicheng; Zheng, Caishang; Ke, Xianliang; Xie, Li; Zheng, Zhenhua; Wu, Xinxing; Wang, Hanzhong

Chen, Wen; He, Wenrong; Cai, Hongbing; Hu, Bicheng; Zheng, Caishang; Ke, Xianliang; Xie, Li; Zheng, Zhenhua; Wu, Xinxing; Wang, Hanzhong.

Afiliação

Chen W; State Key Laboratory of Virology, Institute of Medical Virology, School of Basic Medical Sciences, Wuhan University, Wuhan 430071, China.
He W; Department of Gynaecology and Obstetrics, The First People's Hospital of Jingzhou, Yangtze University, Jingzhou 434000, China.
Cai H; Department of Gynecologic Oncology, Zhongnan Hospital of Wuhan University, Wuhan 430071, China.
Hu B; State Key Laboratory of Virology, Institute of Medical Virology, School of Basic Medical Sciences, Wuhan University, Wuhan 430071, China.
Zheng C; State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, China.
Ke X; State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, China.
Xie L; State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, China.
Zheng Z; State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, China.
Wu X; State Key Laboratory of Virology, Institute of Medical Virology, School of Basic Medical Sciences, Wuhan University, Wuhan 430071, China.
Wang H; State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, China.

Oncotarget ; 8(24): 39417-39429, 2017 Jun 13.

Article em En | MEDLINE | ID: mdl-28455960

Assuntos

Proteínas de Neoplasias/genética; Edição de RNA; Fator de Transcrição STAT3/metabolismo; Neoplasias do Colo do Útero/genética; Neoplasias do Colo do Útero/metabolismo; Adenosina; Adenosina Desaminase/metabolismo; Linhagem Celular Tumoral; Transformação Celular Neoplásica/genética; Transformação Celular Neoplásica/metabolismo; Feminino; Humanos; Inosina; Interleucina-6/metabolismo; Interleucina-6/farmacologia; Mutação; Proteínas de Neoplasias/química; Motivos de Nucleotídeos; Fosforilação; Proteínas de Ligação a RNA/metabolismo; Transdução de Sinais; Neoplasias do Colo do Útero/patologia

Palavras-chave

A-to-I RNA editing; BLCAP gene; STAT3; YXXQ motif; cervical carcinogenesis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias do Colo do Útero / Edição de RNA / Fator de Transcrição STAT3 / Proteínas de Neoplasias Limite: Female / Humans Idioma: En Revista: Oncotarget Ano de publicação: 2017 Tipo de documento: Article País de afiliação: China

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