From the Cover: Comparative Proteomics Reveals Silver Nanoparticles Alter Fatty Acid Metabolism and Amyloid Beta Clearance for Neuronal Apoptosis in a Triple Cell Coculture Model of the Blood-Brain Barrier.

Lin, Ho-Chen; Ho, Ming-Yi; Tsen, Chao-Ming; Huang, Chien-Chu; Wu, Chin-Ching; Huang, Yuh-Jeen; Hsiao, I-Lun; Chuang, Chun-Yu

Lin, Ho-Chen; Ho, Ming-Yi; Tsen, Chao-Ming; Huang, Chien-Chu; Wu, Chin-Ching; Huang, Yuh-Jeen; Hsiao, I-Lun; Chuang, Chun-Yu.

Afiliação

Lin HC; Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, Hsinchu 30013, Taiwan.
Ho MY; Chromatography & Mass Spectrometry, Thermo Fisher Scientific, Taipei 11493, Taiwan.
Tsen CM; Institute of Stem Cell and Translational Cancer Research, Chang Gung Memorial Hospital, Taoyuan 33305, Taiwan.
Huang CC; Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, Hsinchu 30013, Taiwan.
Wu CC; Residue Control Division, Agricultural Chemicals and Toxic Substances Research Institute, Council of Agriculture Executive Yuan, Wufong, Taichung 41358, Taiwan.
Huang YJ; Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, Hsinchu 30013, Taiwan.
Hsiao IL; Department of Public Health, China Medical University, Taichung 40402, Taiwan.
Chuang CY; Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, Hsinchu 30013, Taiwan.

Toxicol Sci ; 158(1): 151-163, 2017 07 01.

Article em En | MEDLINE | ID: mdl-28460142

Assuntos

Peptídeos beta-Amiloides/metabolismo; Apoptose/efeitos dos fármacos; Barreira Hematoencefálica/efeitos dos fármacos; Ácidos Graxos/metabolismo; Nanopartículas Metálicas/toxicidade; Modelos Biológicos; Neurônios/metabolismo; Proteômica; Prata/química; Animais; Astrócitos/citologia; Astrócitos/metabolismo; Técnicas de Cocultura; Citocinas/metabolismo; Azul Evans/metabolismo; Mediadores da Inflamação/metabolismo; Nanopartículas Metálicas/química; Camundongos; Neurônios/citologia; Proteínas de Junções Íntimas/metabolismo

Palavras-chave

Alzheimer's disease; amyloid beta clearance; bloodbrain barrier; proteomic profiling; silver nanoparticles; tight junction protein

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Prata / Barreira Hematoencefálica / Peptídeos beta-Amiloides / Apoptose / Proteômica / Nanopartículas Metálicas / Ácidos Graxos / Modelos Biológicos / Neurônios Limite: Animals Idioma: En Revista: Toxicol Sci Assunto da revista: TOXICOLOGIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Taiwan

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