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Germline TP53 mutations result into a constitutive defect of p53 DNA binding and transcriptional response to DNA damage.
Zerdoumi, Yasmine; Lanos, Raphaël; Raad, Sabine; Flaman, Jean-Michel; Bougeard, Gaëlle; Frebourg, Thierry; Tournier, Isabelle.
Afiliação
  • Zerdoumi Y; Normandie University, UNIROUEN, Inserm U1245 and Rouen University Hospital, Department of Genetics, F 76000, Normandy Centre for Genomic and Personalized Medicine, Rouen, France.
  • Lanos R; Normandie University, UNIROUEN, Inserm U1245 and Rouen University Hospital, Department of Genetics, F 76000, Normandy Centre for Genomic and Personalized Medicine, Rouen, France.
  • Raad S; Normandie University, UNIROUEN, Inserm U1245 and Rouen University Hospital, Department of Genetics, F 76000, Normandy Centre for Genomic and Personalized Medicine, Rouen, France.
  • Flaman JM; Normandie University, UNIROUEN, Inserm U1245 and Rouen University Hospital, Department of Genetics, F 76000, Normandy Centre for Genomic and Personalized Medicine, Rouen, France.
  • Bougeard G; Normandie University, UNIROUEN, Inserm U1245 and Rouen University Hospital, Department of Genetics, F 76000, Normandy Centre for Genomic and Personalized Medicine, Rouen, France.
  • Frebourg T; Normandie University, UNIROUEN, Inserm U1245 and Rouen University Hospital, Department of Genetics, F 76000, Normandy Centre for Genomic and Personalized Medicine, Rouen, France.
  • Tournier I; Normandie University, UNIROUEN, Inserm U1245 and Rouen University Hospital, Department of Genetics, F 76000, Normandy Centre for Genomic and Personalized Medicine, Rouen, France.
Hum Mol Genet ; 26(14): 2812, 2017 07 15.
Article em En | MEDLINE | ID: mdl-28472496

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Hum Mol Genet Assunto da revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: França

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Hum Mol Genet Assunto da revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: França