[Malignant rhabdoid tumor of the kidney: 2 cases and a review of the literature]. / Tumor rabdoide maligno renal: presentación de dos casos y revisión de la literatura.
An Esp Pediatr
; 28(6): 540-4, 1988 Jun.
Article
em Es
| MEDLINE
| ID: mdl-2848433
ABSTRACT
Report of the microscopic, ultrastructural and immunohistochemical findings of two malignant rhabdoid tumors of the kidney in two males aged 2 1/2 and 19 months. The incidence of this tumor in our files is 1.9% of all the renal tumors of infancy. Both cases were formally considered to be rhabdomyosarcomatous variants of nephroblastomas. Microscopically a slightly cohesive polygonal cell proliferation is shown. The cells have intracytoplasmatic hyaline inclusions ultrastructurally identifiable as intermediate filament bundles, showing positivity to vimentin in the immunohistochemical technique. Malignant rhabdoid tumors are referred to as very aggressive tumors with a poor response to treatment and a high mortality rate. Association with central nervous tumors and hypercalcemia has been reported. The clinical and pathologic features make it possible to differentiate them from nephroblastomas, although the histogenesis is not definitely established.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Rabdomiossarcoma
/
Tumor de Wilms
/
Neoplasias Renais
Tipo de estudo:
Prognostic_studies
Limite:
Humans
/
Infant
/
Male
Idioma:
Es
Revista:
An Esp Pediatr
Ano de publicação:
1988
Tipo de documento:
Article