Copper (II)-doped semiconducting polymer dots for nitroxyl imaging in live cells.

Wu, Xu; Wu, Li; Wu, I-Che; Chiu, Daniel T

Wu, Xu; Wu, Li; Wu, I-Che; Chiu, Daniel T.

Afiliação

Wu X; Department of Chemistry and Bioengineering, University of Washington, Seattle, WA, USA.
Wu L; Department of Chemistry and Bioengineering, University of Washington, Seattle, WA, USA.
Wu IC; Department of Chemistry and Bioengineering, University of Washington, Seattle, WA, USA.
Chiu DT; Department of Chemistry and Bioengineering, University of Washington, Seattle, WA, USA.

RSC Adv ; 6(105): 103618-103621, 2016.

Article em En | MEDLINE | ID: mdl-28529727

RESUMO

The first nanoparticle-based fluorescent probe for the specific detection of nitroxyl (HNO) was designed and constructed by doping copper(II) into semiconducting polymer dots (Pdots). The probe turns on and fluoresces in the presence of HNO. We used the new sensor to monitor changes of HNO levels in live cells.

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: RSC Adv Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos

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