The Assessment of Skin Color and Iron Levels in Pediatric Patients with ß-Thalassemia Major Using a Visual Skin Color Chart.
Hemoglobin
; 41(2): 120-123, 2017 Mar.
Article
em En
| MEDLINE
| ID: mdl-28617058
ABSTRACT
Patients with ß-thalassemia major (ß-TM), a disease that emerges due to disorder of hemoglobin (Hb) synthesis, require life-long erythrocyte transfusion. The purpose of this study was to evaluate skin color and iron levels of patients with ß-TM using a visual skin color chart. Each patient's skin color was matched on a skin color chart under a fluorescent lamp by the same physician on each occasion. Iron, iron binding capacity, ferritin and complete blood count (CBC) were studied for each patient enrolled. Colors marked on the visual skin color chart were compared with the laboratory results. Thirty-five patients being monitored at our hospital were included, 19 (54.3%) males and 16 (45.7%) females. The colors marked on the chart darkened as patients aged (p = 0.002, r = 0.49), the frequency of annual transfusions (p = 0.022, r = 0.385), ferritin levels (p < 0.001, r = 0.72) and iron levels increased (p = 0.001, r = 0.538) and as total iron binding capacity (TIBC) decreased (p < 0.001, r = -0.709). On the basis of this study, iron deposition in patients with ß-TM was correlated with the colors on the chart.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Pigmentação da Pele
/
Talassemia beta
/
Ferro
Limite:
Child
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Child, preschool
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Female
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Humans
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Male
Idioma:
En
Revista:
Hemoglobin
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Turquia