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Computational explanation for bioactivation mechanism of targeted anticancer agents mediated by cytochrome P450s: A case of Erlotinib.
Ai, Chun-Zhi; Liu, Yong; Li, Wei; Chen, De-Meng; Zhu, Xin-Xing; Yan, Ya-Wei; Chen, Du-Chu; Jiang, Yi-Zhou.
Afiliação
  • Ai CZ; Institute for Advanced Study, Shenzhen University, Shenzhen, Guangdong, China.
  • Liu Y; Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Optoelectronic Engineering, Shenzhen University, Shenzhen, Guangdong, China.
  • Li W; School of Life Science and Medicine, Dalian University of Technology, Panjin, Liaoning, China.
  • Chen DM; College of Medicine, Yangzhou University, Yangzhou, Jiangsu, China.
  • Zhu XX; Institute for Advanced Study, Shenzhen University, Shenzhen, Guangdong, China.
  • Yan YW; School of Dentistry, University of California, Los Angeles, California, United States of America.
  • Chen DC; Institute for Advanced Study, Shenzhen University, Shenzhen, Guangdong, China.
  • Jiang YZ; Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Optoelectronic Engineering, Shenzhen University, Shenzhen, Guangdong, China.
PLoS One ; 12(6): e0179333, 2017.
Article em En | MEDLINE | ID: mdl-28628631

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sistema Enzimático do Citocromo P-450 / Cloridrato de Erlotinib / Antineoplásicos Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: China

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sistema Enzimático do Citocromo P-450 / Cloridrato de Erlotinib / Antineoplásicos Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: China