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Multitarget drug design strategy in Alzheimer's disease: focus on cholinergic transmission and amyloid-ß aggregation.
Simoni, Elena; Bartolini, Manuela; Abu, Izuddin F; Blockley, Alix; Gotti, Cecilia; Bottegoni, Giovanni; Caporaso, Roberta; Bergamini, Christian; Andrisano, Vincenza; Cavalli, Andrea; Mellor, Ian R; Minarini, Anna; Rosini, Michela.
Afiliação
  • Simoni E; Department of Pharmacy & Biotechnology, Alma Mater Studiorum-University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy.
  • Bartolini M; Department of Pharmacy & Biotechnology, Alma Mater Studiorum-University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy.
  • Abu IF; School of Life Sciences, University of Nottingham, University Park, Nottingham, NG7 2RD, UK.
  • Blockley A; Institute of Medical Science Technology, University of Kuala Lumpur, A1-1, Jalan TKS1, Taman Kajang Sentral, Selangor, 43000 Kajang, Malaysia.
  • Gotti C; School of Life Sciences, University of Nottingham, University Park, Nottingham, NG7 2RD, UK.
  • Bottegoni G; CNR, Institute of Neuroscience, Via Luigi Vanvitelli 32, 20129 Milano, Italy.
  • Caporaso R; Drug Discovery & Development, Istituto Italiano di Tecnologia, via Morego 30, 16163 Genova, Italy.
  • Bergamini C; Department of Pharmacy & Biotechnology, Alma Mater Studiorum-University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy.
  • Andrisano V; Department of Pharmacy & Biotechnology, Alma Mater Studiorum-University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy.
  • Cavalli A; Department for Life Quality Studies, Alma Mater Studiorum-University of Bologna, Corso d'Augusto 237, 47921 Rimini, Italy.
  • Mellor IR; Department of Pharmacy & Biotechnology, Alma Mater Studiorum-University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy.
  • Minarini A; Drug Discovery & Development, Istituto Italiano di Tecnologia, via Morego 30, 16163 Genova, Italy.
  • Rosini M; School of Life Sciences, University of Nottingham, University Park, Nottingham, NG7 2RD, UK.
Future Med Chem ; 9(10): 953-963, 2017 06.
Article em En | MEDLINE | ID: mdl-28632446
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Desenho de Fármacos / Inibidores da Colinesterase / Peptídeos beta-Amiloides / Transmissão Sináptica / Doença de Alzheimer Limite: Humans Idioma: En Revista: Future Med Chem Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Itália
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Desenho de Fármacos / Inibidores da Colinesterase / Peptídeos beta-Amiloides / Transmissão Sináptica / Doença de Alzheimer Limite: Humans Idioma: En Revista: Future Med Chem Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Itália