Mithramycin has inhibitory effects on gliostatin and matrix metalloproteinase expression induced by gliostatin in rheumatoid fibroblast-like synoviocytes.

Tatematsu, Naoe; Waguri-Nagaya, Yuko; Kawaguchi, Yohei; Oguri, Yusuke; Ikuta, Kenji; Kobayashi, Masaaki; Nozaki, Masahiro; Asai, Kiyofumi; Aoyama, Mineyoshi; Otsuka, Takanobu

Tatematsu, Naoe; Waguri-Nagaya, Yuko; Kawaguchi, Yohei; Oguri, Yusuke; Ikuta, Kenji; Kobayashi, Masaaki; Nozaki, Masahiro; Asai, Kiyofumi; Aoyama, Mineyoshi; Otsuka, Takanobu.

Afiliação

Tatematsu N; a Department of Orthopaedic Surgery , Nagoya City University Graduate School of Medical Sciences , Nagoya , Japan.
Waguri-Nagaya Y; b Department of Joint Surgery for Rheumatic Diseases , Nagoya City University Graduate School of Medical Sciences , Nagoya , Japan.
Kawaguchi Y; a Department of Orthopaedic Surgery , Nagoya City University Graduate School of Medical Sciences , Nagoya , Japan.
Oguri Y; a Department of Orthopaedic Surgery , Nagoya City University Graduate School of Medical Sciences , Nagoya , Japan.
Ikuta K; a Department of Orthopaedic Surgery , Nagoya City University Graduate School of Medical Sciences , Nagoya , Japan.
Kobayashi M; a Department of Orthopaedic Surgery , Nagoya City University Graduate School of Medical Sciences , Nagoya , Japan.
Nozaki M; a Department of Orthopaedic Surgery , Nagoya City University Graduate School of Medical Sciences , Nagoya , Japan.
Asai K; c Department of Molecular Neurobiology , Nagoya City University Graduate School of Medical Sciences , Nagoya , Japan.
Aoyama M; d Department of Pathobiology , Nagoya City University Graduate School of Pharmaceutical Sciences , Nagoya , Japan.
Otsuka T; a Department of Orthopaedic Surgery , Nagoya City University Graduate School of Medical Sciences , Nagoya , Japan.

Mod Rheumatol ; 28(3): 495-505, 2018 May.

Article em En | MEDLINE | ID: mdl-28741989

Assuntos

Artrite Reumatoide/metabolismo; Metaloproteinases da Matriz/metabolismo; Plicamicina/farmacologia; Sinoviócitos/efeitos dos fármacos; Timidina Fosforilase/metabolismo; Idoso; Idoso de 80 Anos ou mais; Antirreumáticos/farmacologia; Artrite Reumatoide/patologia; Células Cultivadas; Feminino; Humanos; Masculino; Metaloproteinases da Matriz/genética; Pessoa de Meia-Idade; Sinoviócitos/metabolismo; Timidina Fosforilase/genética

Palavras-chave

Fibroblast-like synoviocytes; gliostatin; matrix metalloproteinases; mithramycin; rheumatoid arthritis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Artrite Reumatoide / Timidina Fosforilase / Plicamicina / Metaloproteinases da Matriz / Sinoviócitos Limite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Mod Rheumatol Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Japão

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