HER2 mutations in lung adenocarcinomas: A report from the Lung Cancer Mutation Consortium.

Pillai, Rathi N; Behera, Madhusmita; Berry, Lynne D; Rossi, Mike R; Kris, Mark G; Johnson, Bruce E; Bunn, Paul A; Ramalingam, Suresh S; Khuri, Fadlo R

Pillai, Rathi N; Behera, Madhusmita; Berry, Lynne D; Rossi, Mike R; Kris, Mark G; Johnson, Bruce E; Bunn, Paul A; Ramalingam, Suresh S; Khuri, Fadlo R.

Afiliação

Pillai RN; Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University, Atlanta, Georgia.
Behera M; Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University, Atlanta, Georgia.
Berry LD; Vanderbilt Center for Quantitative Sciences, Vanderbilt-Ingram Cancer Center, Nashville, Tennessee.
Rossi MR; Division of Cancer Biology, Department of Radiation Oncology, Emory University, Atlanta, Georgia.
Kris MG; Thoracic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, New York.
Johnson BE; Clinical Research, Dana-Farber Cancer Institute, Boston, Massachusetts.
Bunn PA; Division of Medical Oncology, University of Colorado Cancer Center, Aurora, Colorado.
Ramalingam SS; Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University, Atlanta, Georgia.
Khuri FR; Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University, Atlanta, Georgia.

Cancer ; 123(21): 4099-4105, 2017 Nov 01.

Article em En | MEDLINE | ID: mdl-28743157

Assuntos

Adenocarcinoma/genética; Genes erbB-2/genética; Neoplasias Pulmonares/genética; Mutagênese Insercional; Adenocarcinoma/mortalidade; Adenocarcinoma/patologia; Adenocarcinoma/terapia; Adulto; Idoso; Intervalos de Confiança; Bases de Dados Genéticas; Transição Epitelial-Mesenquimal/genética; Éxons; Feminino; Humanos; Neoplasias Pulmonares/mortalidade; Neoplasias Pulmonares/patologia; Neoplasias Pulmonares/terapia; Masculino; Pessoa de Meia-Idade; Mutagênese Insercional/estatística & dados numéricos; Mutação; Análise de Sobrevida

Palavras-chave

Lung Cancer Mutation Consortium (LCMC); human epidermal growth factor receptor 2 (HER2); lung adenocarcinoma; multiplexed sequencing; targeted therapy

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Adenocarcinoma / Mutagênese Insercional / Genes erbB-2 / Neoplasias Pulmonares Tipo de estudo: Risk_factors_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Cancer Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Geórgia

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