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Target specificity, in vivo pharmacokinetics, and efficacy of the putative STAT3 inhibitor LY5 in osteosarcoma, Ewing's sarcoma, and rhabdomyosarcoma.
Yu, Peter Y; Gardner, Heather L; Roberts, Ryan; Cam, Hakan; Hariharan, Seethalakshmi; Ren, Ling; LeBlanc, Amy K; Xiao, Hui; Lin, Jiayuh; Guttridge, Denis C; Mo, Xiaokui; Bennett, Chad E; Coss, Christopher C; Ling, Yonghua; Phelps, Mitch A; Houghton, Peter; London, Cheryl A.
Afiliação
  • Yu PY; Medical Student Research Program, The Ohio State University College of Medicine, The Ohio State University Wexner Medical Center, Columbus, Ohio, United States of America.
  • Gardner HL; Department of Veterinary Biosciences and Clinical Sciences, The Ohio State University, Columbus, Ohio, United States of America.
  • Roberts R; Center for Childhood Cancer, Nationwide Children's Hospital, Columbus, Ohio, United States of America.
  • Cam H; Center for Childhood Cancer, Nationwide Children's Hospital, Columbus, Ohio, United States of America.
  • Hariharan S; Greehey Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, Texas, United States of America.
  • Ren L; Comparative Oncology Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
  • LeBlanc AK; Comparative Oncology Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Xiao H; Center for Childhood Cancer, Nationwide Children's Hospital, Columbus, Ohio, United States of America.
  • Lin J; Center for Childhood Cancer, Nationwide Children's Hospital, Columbus, Ohio, United States of America.
  • Guttridge DC; Arthur G. James Comprehensive Cancer Center, The Ohio State University Wexner Medical Center, Columbus, Ohio, United States of America.
  • Mo X; Department of Cancer Biology and Genetics, The Ohio State University Wexner Medical Center, Columbus, Ohio, United States of America.
  • Bennett CE; Center for Biostatistics, The Ohio State University Wexner Medical Center, Columbus, Ohio, United States of America.
  • Coss CC; Medicinal Chemistry Shared Resource, The Ohio State University Wexner Medical Center, Columbus, Ohio, United States of America.
  • Ling Y; Pharmacoanalytic Shared Resource, The Ohio State University Wexner Medical Center, Columbus, Ohio, United States of America.
  • Phelps MA; Pharmacoanalytic Shared Resource, The Ohio State University Wexner Medical Center, Columbus, Ohio, United States of America.
  • Houghton P; Pharmacoanalytic Shared Resource, The Ohio State University Wexner Medical Center, Columbus, Ohio, United States of America.
  • London CA; Greehey Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, Texas, United States of America.
PLoS One ; 12(7): e0181885, 2017.
Article em En | MEDLINE | ID: mdl-28750090
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Rabdomiossarcoma / Sarcoma de Ewing / Sulfonamidas / Osteossarcoma / Fator de Transcrição STAT3 / Aminopiridinas Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Rabdomiossarcoma / Sarcoma de Ewing / Sulfonamidas / Osteossarcoma / Fator de Transcrição STAT3 / Aminopiridinas Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos