Pheochromocytoma with Synchronous Ipsilateral Adrenal Cortical Adenoma.
World J Surg
; 41(12): 3147-3153, 2017 12.
Article
em En
| MEDLINE
| ID: mdl-28762170
ABSTRACT
BACKGROUND:
Pheochromocytoma with synchronous ipsilateral adrenal cortical adenoma (PSCA) may present with mixed clinical, biochemical, and radiological features characteristic to each neoplasm subtype.METHODS:
All patients with a pathological diagnosis of pheochromocytoma were evaluated for an ipsilateral cortical adenoma from 1994 through 2015. Retrospectively extracted data included indications for adrenalectomy, diagnostic workup (biochemical and radiographic), operative characteristics, pathological findings, and postoperative complications.RESULTS:
Sixteen of 413 patients (4%) undergoing adrenalectomy for pheochromocytoma had a PSCA. Median patient age was 57.7 years (IQR 50.1, 63.1); 50% were male. On imaging, 75% of the adrenal neoplasms were found incidentally and only 50% were reported to have a synchronous ipsilateral neoplasm based on imaging findings. Clinically important cortical hormone secretion was diagnosed in 38% of these patients; 25% had glucocorticoid secretory autonomy; and 13% had primary aldosteronism.CONCLUSION:
Physicians should be aware that adrenal neoplasms with mixed diagnostic findings may represent PSCA. Evaluation should be performed on this co-occurrence to prevent perioperative complications from resection of an unexpected secretory cortical neoplasm.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Feocromocitoma
/
Corticosteroides
/
Neoplasias do Córtex Suprarrenal
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Neoplasias das Glândulas Suprarrenais
/
Adenoma Adrenocortical
/
Neoplasias Primárias Múltiplas
Tipo de estudo:
Etiology_studies
/
Observational_studies
Limite:
Adult
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Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
World J Surg
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Estados Unidos