Altered vulnerability to asthma at various levels of ambient Benzo[a]Pyrene by CTLA4, STAT4 and CYP2E1 polymorphisms.

Choi, Hyunok; Tabashidze, Nana; Rossner, Pavel; Dostal, Miroslav; Pastorkova, Anna; Kong, Sek Won; Gmuender, Hans; Sram, Radim J

Choi, Hyunok; Tabashidze, Nana; Rossner, Pavel; Dostal, Miroslav; Pastorkova, Anna; Kong, Sek Won; Gmuender, Hans; Sram, Radim J.

Afiliação

Choi H; Departments of Environmental Health Sciences, Epidemiology, and Biostatistics University at Albany School of Public Health, One University Place, Room 153, Rensselaer, NY 12144-3456, USA. Electronic address: hchoi@albany.edu.
Tabashidze N; Department of Genetic Ecotoxicology, Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, v.v.i., Vídenská 1083, 142 20, Prague 4, Czech Republic. Electronic address: nanatabashidze@yahoo.com.
Rossner P; Department of Genetic Ecotoxicology, Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, v.v.i., Vídenská 1083, 142 20, Prague 4, Czech Republic. Electronic address: prossner@biomed.cas.cz.
Dostal M; Department of Genetic Ecotoxicology, Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, v.v.i., Vídenská 1083, 142 20, Prague 4, Czech Republic. Electronic address: dostal@biomed.cas.cz.
Pastorkova A; Department of Genetic Ecotoxicology, Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, v.v.i., Vídenská 1083, 142 20, Prague 4, Czech Republic.
Kong SW; Boston Children's Hospital, 300 Longwood Ave, Boston, MA 02115, USA. Electronic address: sekwon.kong@childrens.harvard.edu.
Gmuender H; Genedata AG, Margarethenstrasse 38, CH-4053, Basel, Switzerland. Electronic address: hans.gmuender@genedata.com.
Sram RJ; Department of Genetic Ecotoxicology, Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, v.v.i., Vídenská 1083, 142 20, Prague 4, Czech Republic. Electronic address: sram@biomed.cas.cz.

Environ Pollut ; 231(Pt 1): 1134-1144, 2017 Dec.

Article em En | MEDLINE | ID: mdl-28807506

Assuntos

Poluição do Ar/análise; Asma/genética; Benzo(a)pireno/análise; Antígeno CTLA-4/genética; Citocromo P-450 CYP2E1/genética; Predisposição Genética para Doença; Fator de Transcrição STAT4/genética; Asma/induzido quimicamente; Estudos de Casos e Controles; Criança; República Tcheca; Relação Dose-Resposta a Droga; Exposição Ambiental/análise; Feminino; Interação Gene-Ambiente; Genótipo; Humanos; Masculino; Polimorfismo de Nucleotídeo Único; População Rural; População Urbana

Palavras-chave

Air pollution; Asthma; Gene-environment interaction; Polycyclic aromatic hydrocarbon; Single nucleotide polymorphism

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Asma / Benzo(a)pireno / Citocromo P-450 CYP2E1 / Predisposição Genética para Doença / Poluição do Ar / Fator de Transcrição STAT4 / Antígeno CTLA-4 Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Child / Female / Humans / Male País/Região como assunto: Europa Idioma: En Revista: Environ Pollut Assunto da revista: SAUDE AMBIENTAL Ano de publicação: 2017 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google