Fluorescent probes for selective protein labeling in lysosomes: a case of &#945;-galactosidase A.

Bohl, Cornelius; Pomorski, Adam; Seemann, Susanne; Knospe, Anne-Marie; Zheng, Chaonan; Krezel, Artur; Rolfs, Arndt; Lukas, Jan

Fluorescent probes for selective protein labeling in lysosomes: a case of α-galactosidase A.

Bohl, Cornelius; Pomorski, Adam; Seemann, Susanne; Knospe, Anne-Marie; Zheng, Chaonan; Krezel, Artur; Rolfs, Arndt; Lukas, Jan.

Afiliação

Bohl C; Albrecht-Kossel-Institute for Neuroregeneration, Rostock University Medical Center, Rostock, Mecklenburg-Vorpommern, Germany; and.
Pomorski A; Department of Chemical Biology, Faculty of Biotechnology, University of Wroclaw, Wroclaw, Poland.
Seemann S; Albrecht-Kossel-Institute for Neuroregeneration, Rostock University Medical Center, Rostock, Mecklenburg-Vorpommern, Germany; and.
Knospe AM; Albrecht-Kossel-Institute for Neuroregeneration, Rostock University Medical Center, Rostock, Mecklenburg-Vorpommern, Germany; and.
Zheng C; Albrecht-Kossel-Institute for Neuroregeneration, Rostock University Medical Center, Rostock, Mecklenburg-Vorpommern, Germany; and.
Krezel A; Department of Chemical Biology, Faculty of Biotechnology, University of Wroclaw, Wroclaw, Poland.
Rolfs A; Albrecht-Kossel-Institute for Neuroregeneration, Rostock University Medical Center, Rostock, Mecklenburg-Vorpommern, Germany; and.
Lukas J; Albrecht-Kossel-Institute for Neuroregeneration, Rostock University Medical Center, Rostock, Mecklenburg-Vorpommern, Germany; and jan.lukas@med.uni-rostock.de.

FASEB J ; 31(12): 5258-5267, 2017 12.

Article em En | MEDLINE | ID: mdl-28821638

Assuntos

Corantes Fluorescentes/química; Lisossomos/metabolismo; Imagem Molecular/métodos; alfa-Galactosidase/metabolismo; Animais; Western Blotting; Células COS; Chlorocebus aethiops; Concentração de Íons de Hidrogênio; Transporte Proteico

Palavras-chave

Anderson-Fabry disease; biarsenical probes; live-cell imaging; protein trafficking; tetracysteine tag

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Alfa-Galactosidase / Imagem Molecular / Corantes Fluorescentes / Lisossomos Limite: Animals Idioma: En Revista: FASEB J Assunto da revista: BIOLOGIA / FISIOLOGIA Ano de publicação: 2017 Tipo de documento: Article

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