Lipocalin 2 negatively regulates cell proliferation and epithelial to mesenchymal transition through changing metabolic gene expression in colorectal cancer.

Kim, Se-Lim; Lee, Soo Teik; Min, In Suk; Park, Young Ran; Lee, Ju Hyung; Kim, Dae-Ghon; Kim, Sang-Wook

Kim, Se-Lim; Lee, Soo Teik; Min, In Suk; Park, Young Ran; Lee, Ju Hyung; Kim, Dae-Ghon; Kim, Sang-Wook.

Afiliação

Kim SL; Department of Internal Medicine Research Institute of Clinical Medicine, Chonbuk National University Hospital, Chonbuk National University Medical School, Jeonju, Korea.
Lee ST; Biomedical Research Institute, Chonbuk National University Hospital, Chonbuk National University Medical School, Jeonju, Korea.
Min IS; Department of Internal Medicine Research Institute of Clinical Medicine, Chonbuk National University Hospital, Chonbuk National University Medical School, Jeonju, Korea.
Park YR; Biomedical Research Institute, Chonbuk National University Hospital, Chonbuk National University Medical School, Jeonju, Korea.
Lee JH; Department of Internal Medicine Research Institute of Clinical Medicine, Chonbuk National University Hospital, Chonbuk National University Medical School, Jeonju, Korea.
Kim DG; Biomedical Research Institute, Chonbuk National University Hospital, Chonbuk National University Medical School, Jeonju, Korea.
Kim SW; Department of Internal Medicine Research Institute of Clinical Medicine, Chonbuk National University Hospital, Chonbuk National University Medical School, Jeonju, Korea.

Cancer Sci ; 108(11): 2176-2186, 2017 Nov.

Article em En | MEDLINE | ID: mdl-28859238

Assuntos

Proliferação de Células/genética; Neoplasias Colorretais/genética; Metabolismo Energético/genética; Transição Epitelial-Mesenquimal/genética; Lipocalina-2/genética; Idoso; Linhagem Celular Tumoral; Movimento Celular/genética; Neoplasias Colorretais/patologia; Feminino; Regulação Neoplásica da Expressão Gênica; Técnicas de Silenciamento de Genes; Glucose/metabolismo; Humanos; Masculino; Transdução de Sinais

Palavras-chave

Colorectal cancer; Warburg effect; epithelial-mesenchymal transition; glucose metabolism; lipocalin 2; proliferation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Proliferação de Células / Metabolismo Energético / Transição Epitelial-Mesenquimal / Lipocalina-2 Limite: Aged / Female / Humans / Male Idioma: En Revista: Cancer Sci Ano de publicação: 2017 Tipo de documento: Article

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