Cost-effective screening of DNMT3A coding sequence identifies somatic mutation in pediatric T-cell acute lymphoblastic leukemia.

Szarzynska-Zawadzka, Bronislawa; Kosmalska, Maria; Sedek, Lukasz; Sonsala, Alicja; Twardoch, Magdalena; Kowalczyk, Jerzy R; Szczepanski, Tomasz; Witt, Michal; Dawidowska, Malgorzata

Szarzynska-Zawadzka, Bronislawa; Kosmalska, Maria; Sedek, Lukasz; Sonsala, Alicja; Twardoch, Magdalena; Kowalczyk, Jerzy R; Szczepanski, Tomasz; Witt, Michal; Dawidowska, Malgorzata.

Afiliação

Szarzynska-Zawadzka B; Institute of Human Genetics Polish Academy of Sciences, Poznan, Poland.
Kosmalska M; Institute of Human Genetics Polish Academy of Sciences, Poznan, Poland.
Sedek L; Department of Microbiology and Immunology, Medical University of Silesia in Katowice, Zabrze, Poland.
Sonsala A; Department of Pediatric Hematology and Oncology, Medical University of Silesia in Katowice, Zabrze, Poland.
Twardoch M; Department of Pediatric Hematology and Oncology, Medical University of Silesia in Katowice, Zabrze, Poland.
Kowalczyk JR; Department of Pediatric Hematology, Oncology and Transplantology, Cytogenetic Laboratory, Children's University Hospital, Medical University of Lublin, Lublin, Poland.
Szczepanski T; Department of Pediatric Hematology and Oncology, Medical University of Silesia in Katowice, Zabrze, Poland.
Witt M; Institute of Human Genetics Polish Academy of Sciences, Poznan, Poland.
Dawidowska M; Institute of Human Genetics Polish Academy of Sciences, Poznan, Poland.

Eur J Haematol ; 99(6): 514-519, 2017 Dec.

Article em En | MEDLINE | ID: mdl-28905428

Assuntos

DNA (Citosina-5-)-Metiltransferases/genética; Éxons; Mutação; Leucemia-Linfoma Linfoblástico de Células T Precursoras/genética; Adolescente; Fatores Etários; Criança; Pré-Escolar; Análise Custo-Benefício; DNA Metiltransferase 3A; Análise Mutacional de DNA/economia; Análise Mutacional de DNA/métodos; Feminino; Humanos; Lactente; Recém-Nascido; Masculino; Leucemia-Linfoma Linfoblástico de Células T Precursoras/diagnóstico

Palavras-chave

DNMT3A; high-resolution melt; mutation screening; pediatric T-cell acute lymphoblastic leukemia; prognostic factors

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Éxons / DNA (Citosina-5-)-Metiltransferases / Leucemia-Linfoma Linfoblástico de Células T Precursoras / Mutação Tipo de estudo: Diagnostic_studies / Health_economic_evaluation / Prognostic_studies / Screening_studies Limite: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male / Newborn Idioma: En Revista: Eur J Haematol Assunto da revista: HEMATOLOGIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Polônia

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