Nasal Continuous Positive Airway Pressure in Bronchiolitis: A Randomized Controlled Trial.
Indian Pediatr
; 55(1): 27-30, 2018 01 15.
Article
em En
| MEDLINE
| ID: mdl-28952459
ABSTRACT
OBJECTIVE:
To evaluate the efficacy of nasal continuous positive airway pressure (nCPAP) in decreasing respiratory distress in bronchiolitis.DESIGN:
Randomized controlled trial.SETTING:
Tertiary-care hospital in New Delhi, India.Participants:
72 infants (age <1y) hospitalized with a clinical diagnosis of bronchiolitis were randomized to receive standard care, or nCPAP in addition to standard care, in the first hour after admission. 23 parents refused to give consent for participation. 2 infants did not tolerate nCPAP.PARTICIPANTS:
72 infants (age <1y) hospitalized with a clinical diagnosis of bronchiolitis were randomized to receive standard care, or nCPAP in addition to standard care, in the first hour after admission. 23 parents refused to give consent for participation. 2 infants did not tolerate nCPAP. INTERVENTION The outcome was assessed after 60 minutes. If nCPAP was not tolerated or the distress increased, the infant was switched to standard care. Analysis was done on intention-to-treat basis. MAIN OUTCOMEMEASURES:
Change in respiratory rate, Silverman-Anderson score and a Modified Pediatric Society of New Zealand Severity Score.RESULTS:
14 out of 32 in nCPAP group and 5 out of 35 in standard care group had change in respiratory rate ≥10 (P=0.008). The mean (SD) change in respiratory rate [8.0 (5.8) vs 5.1 (4.0), P=0.02] in Silverman-Anderson score [0.78 (0.87) vs 0.39 (0.73), P=0.029] and in Modified Pediatric Society of New Zealand Severity Score [2.5 (3.01) vs. 1.08 (1.3), P=0.012] were significantly different in the nCPAP and standard care groups, respectively.CONCLUSIONS:
nCPAP helped reduce respiratory distress significantly compared to standard care.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Bronquiolite
/
Pressão Positiva Contínua nas Vias Aéreas
/
Ventilação não Invasiva
Tipo de estudo:
Clinical_trials
Limite:
Female
/
Humans
/
Infant
/
Male
/
Newborn
País/Região como assunto:
Asia
Idioma:
En
Revista:
Indian Pediatr
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
Índia