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RNAi-based treatment of chronically infected patients and chimpanzees reveals that integrated hepatitis B virus DNA is a source of HBsAg.
Wooddell, Christine I; Yuen, Man-Fung; Chan, Henry Lik-Yuen; Gish, Robert G; Locarnini, Stephen A; Chavez, Deborah; Ferrari, Carlo; Given, Bruce D; Hamilton, James; Kanner, Steven B; Lai, Ching-Lung; Lau, Johnson Y N; Schluep, Thomas; Xu, Zhao; Lanford, Robert E; Lewis, David L.
Afiliação
  • Wooddell CI; Arrowhead Pharmaceuticals, 502 South Rosa Road, Madison, WI 53719, USA. cwooddell@arrowheadpharma.com.
  • Yuen MF; Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong, China.
  • Chan HL; Department of Medicine and Therapeutics and Institute of Digestive Disease, Chinese University of Hong Kong, Hong Kong, China.
  • Gish RG; Liver Transplant Program, Stanford University Medical Center, San Diego, CA 92037, USA.
  • Locarnini SA; Victorian Infectious Diseases Reference Laboratory, Melbourne, Victoria 3000, Australia.
  • Chavez D; WHO Regional Reference Laboratory for Hepatitis B, Doherty Institute, Melbourne, Victoria, Australia.
  • Ferrari C; Southwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, TX 78227, USA.
  • Given BD; Unit of Infectious Diseases and Hepatology, University of Parma, Parma 43126, Italy.
  • Hamilton J; Azienda Ospedaliero-Universitaria of Parma, Parma 43126, Italy.
  • Kanner SB; Arrowhead Pharmaceuticals, 502 South Rosa Road, Madison, WI 53719, USA.
  • Lai CL; Arrowhead Pharmaceuticals, 225 South Lake Avenue, Suite 1050, Pasadena, CA 91101, USA.
  • Lau JYN; Arrowhead Pharmaceuticals, 502 South Rosa Road, Madison, WI 53719, USA.
  • Schluep T; Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong, China.
  • Xu Z; Hong Kong Polytechnic University, Hong Kong, China.
  • Lanford RE; Arrowhead Pharmaceuticals, 225 South Lake Avenue, Suite 1050, Pasadena, CA 91101, USA.
  • Lewis DL; Arrowhead Pharmaceuticals, 502 South Rosa Road, Madison, WI 53719, USA.
Sci Transl Med ; 9(409)2017 Sep 27.
Article em En | MEDLINE | ID: mdl-28954926
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: DNA Viral / Integração Viral / Hepatite B Crônica / Interferência de RNA / Antígenos de Superfície da Hepatite B Tipo de estudo: Clinical_trials Limite: Animals / Humans Idioma: En Revista: Sci Transl Med Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: DNA Viral / Integração Viral / Hepatite B Crônica / Interferência de RNA / Antígenos de Superfície da Hepatite B Tipo de estudo: Clinical_trials Limite: Animals / Humans Idioma: En Revista: Sci Transl Med Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos