Effect of BIX-01294 on proliferation, apoptosis and histone methylation of acute T lymphoblastic leukemia cells.

Huang, Yiqun; Zou, Yong; Lin, Luhui; Ma, Xudong; Huang, Xiaohong

Huang, Yiqun; Zou, Yong; Lin, Luhui; Ma, Xudong; Huang, Xiaohong.

Afiliação

Huang Y; Department of Hematology, Zhangzhou Affiliated Hospital of Fujian Medical University, Zhangzhou, Fujian 363000, China.
Zou Y; Department of Hematology, Zhangzhou Affiliated Hospital of Fujian Medical University, Zhangzhou, Fujian 363000, China.
Lin L; Department of Hematology, Zhangzhou Affiliated Hospital of Fujian Medical University, Zhangzhou, Fujian 363000, China.
Ma X; Department of Hematology, Zhangzhou Affiliated Hospital of Fujian Medical University, Zhangzhou, Fujian 363000, China.
Huang X; Department of Pharmacy, Zhangzhou Affiliated Hospital of Fujian Medical University, No. 59 Shengli Road, Zhangzhou, Fujian 363000, China. Electronic address: XiaohongHuang2017@163.com.

Leuk Res ; 62: 34-39, 2017 11.

Article em En | MEDLINE | ID: mdl-28982057

Assuntos

Antineoplásicos/farmacologia; Apoptose/efeitos dos fármacos; Azepinas/farmacologia; Proliferação de Células/efeitos dos fármacos; Metilação de DNA/efeitos dos fármacos; Leucemia-Linfoma Linfoblástico de Células T Precursoras; Quinazolinas/farmacologia; Linhagem Celular Tumoral; Histonas/efeitos dos fármacos; Humanos

Palavras-chave

Acute T lymphocytic leukemia; BIX-01294; Epigenetics; G9a; Histone acetylation; Histone methylation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quinazolinas / Azepinas / Apoptose / Metilação de DNA / Proliferação de Células / Leucemia-Linfoma Linfoblástico de Células T Precursoras / Antineoplásicos Limite: Humans Idioma: En Revista: Leuk Res Ano de publicação: 2017 Tipo de documento: Article País de afiliação: China

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