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Dataset on the synthesis and characterization of boron fenbufen and its F-18 labeled homolog.
Yeh, Chun-Nan; Chang, Chi-Wei; Chung, Yi-Hsiu; Tien, Shi-Wei; Chen, Yong-Ren; Chen, Tsung-Wen; Huang, Ying-Cheng; Wang, Hsin-Ell; Chou, You-Cheng; Chen, Ming-Huang; Chiang, Kun-Chun; Huang, Wen-Sheng; Yu, Chung-Shan.
Afiliação
  • Yeh CN; Department of Surgery, Liver Research Center, Chang-Gung Memorial Hospital at Linkou, Chang Gung University, Taiwan.
  • Chang CW; Department of Nuclear Medicine, Veterans General Hospital at Taipei, Taiwan.
  • Chung YH; Center for Advanced Molecular Imaging and Translation, Chang Gung Memorial Hospital, Taiwan.
  • Tien SW; Department of Biomedical Engineering and Environmental Sciences, National Tsinghua University, Hsinchu 300, Taiwan.
  • Chen YR; Department of Biomedical Engineering and Environmental Sciences, National Tsinghua University, Hsinchu 300, Taiwan.
  • Chen TW; Department of Surgery, Liver Research Center, Chang-Gung Memorial Hospital at Linkou, Chang Gung University, Taiwan.
  • Huang YC; Department of Neurosurgery, Chang-Gung Memorial Hospital at Linkou, Chang Gung University, Taiwan.
  • Wang HE; Department of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei, Taiwan.
  • Chou YC; Department of Biomedical Engineering and Environmental Sciences, National Tsinghua University, Hsinchu 300, Taiwan.
  • Chen MH; Department of Medical Radiology, Yang-Ming University at Taipei, Taiwan.
  • Chiang KC; Department of Surgery, Chang-Gung Memorial Hospital at Keelung, Chang Gung University, Taiwan.
  • Huang WS; Department of Nuclear Medicine, Veterans General Hospital at Taipei, Taiwan.
  • Yu CS; Department of Biomedical Engineering and Environmental Sciences, National Tsinghua University, Hsinchu 300, Taiwan.
Data Brief ; 15: 174-202, 2017 Dec.
Article em En | MEDLINE | ID: mdl-29021997
ABSTRACT
The data presented in this article are related to the research article entitled "Synthesis and Characterization of Boron Fenbufen and its F-18 Labeled Homolog for Boron Neutron Capture Therapy of COX-2 Overexpressed Cholangiocarcinoma". The contents of the data article include 1) the set up for performing in vitro binding assay, 2) 1H-, 13C- and 19F-NMR of compounds described in main text, 3) HPLC chromatogram of the fluorination mixtures, 4) data of in vitro stability test, cell survival assay, western blot and PCR analysis, 5) the modules for fixing the two CCA rats for BNCT, and 6) bar diagram for tumor reduction using [18F]FDG-PET 24 h post treatment with BNCT.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Data Brief Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Taiwan

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Data Brief Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Taiwan