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Reducing sarcolipin expression mitigates Duchenne muscular dystrophy and associated cardiomyopathy in mice.
Voit, Antanina; Patel, Vishwendra; Pachon, Ronald; Shah, Vikas; Bakhutma, Mohammad; Kohlbrenner, Erik; McArdle, Joseph J; Dell'Italia, Louis J; Mendell, Jerry R; Xie, Lai-Hua; Hajjar, Roger J; Duan, Dongsheng; Fraidenraich, Diego; Babu, Gopal J.
Afiliação
  • Voit A; Department of Cell Biology and Molecular Medicine, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ, 07103, USA.
  • Patel V; Department of Pharmacology, Physiology and Neuroscience, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ, 07103, USA.
  • Pachon R; Department of Cell Biology and Molecular Medicine, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ, 07103, USA.
  • Shah V; Department of Cell Biology and Molecular Medicine, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ, 07103, USA.
  • Bakhutma M; Department of Cell Biology and Molecular Medicine, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ, 07103, USA.
  • Kohlbrenner E; Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • McArdle JJ; Department of Pharmacology, Physiology and Neuroscience, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ, 07103, USA.
  • Dell'Italia LJ; Department of Medicine, University of Alabama at Birmingham, and Birmingham VA Medical Center, Birmingham, AL, 35294, USA.
  • Mendell JR; Department of Pediatrics and Department of Neurology, Ohio State University Research Institute at Nationwide Children's Hospital, Columbus, OH, 43205, USA.
  • Xie LH; Department of Cell Biology and Molecular Medicine, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ, 07103, USA.
  • Hajjar RJ; Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Duan D; Department of Molecular Microbiology and Immunology, Neurology, Bioengineering, Biomedical Sciences, The University of Missouri, Columbia, MO, 65212, USA.
  • Fraidenraich D; Department of Cell Biology and Molecular Medicine, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ, 07103, USA.
  • Babu GJ; Department of Cell Biology and Molecular Medicine, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ, 07103, USA. babugo@njms.rutgers.edu.
Nat Commun ; 8(1): 1068, 2017 10 20.
Article em En | MEDLINE | ID: mdl-29051551
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteolipídeos / Terapia Genética / Regulação da Expressão Gênica / Distrofia Muscular de Duchenne / Inativação Gênica / Proteínas Musculares / Cardiomiopatias Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteolipídeos / Terapia Genética / Regulação da Expressão Gênica / Distrofia Muscular de Duchenne / Inativação Gênica / Proteínas Musculares / Cardiomiopatias Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos