Studies on the chemical and intestinal metabolic profiles of Polygalae Radix by using UHPLC-IT-MS<sup>n</sup> and UHPLC-Q-TOF-MS method coupled with intestinal bacteria incubation model in vitro.

Feng, Gui-Fang; Liu, Shu; Pi, Zi-Feng; Song, Feng-Rui; Liu, Zhi-Qiang

Studies on the chemical and intestinal metabolic profiles of Polygalae Radix by using UHPLC-IT-MSⁿ and UHPLC-Q-TOF-MS method coupled with intestinal bacteria incubation model in vitro.

Feng, Gui-Fang; Liu, Shu; Pi, Zi-Feng; Song, Feng-Rui; Liu, Zhi-Qiang.

Afiliação

Feng GF; National Center of Mass Spectrometry in Changchun & Jilin Province Key Laboratory of Chinese Medicine Chemistry and Mass Spectrometry & Chemical Biology Laboratory, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022, PR China; University of Science and T
Liu S; National Center of Mass Spectrometry in Changchun & Jilin Province Key Laboratory of Chinese Medicine Chemistry and Mass Spectrometry & Chemical Biology Laboratory, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022, PR China. Electronic address: mslab20
Pi ZF; National Center of Mass Spectrometry in Changchun & Jilin Province Key Laboratory of Chinese Medicine Chemistry and Mass Spectrometry & Chemical Biology Laboratory, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022, PR China.
Song FR; National Center of Mass Spectrometry in Changchun & Jilin Province Key Laboratory of Chinese Medicine Chemistry and Mass Spectrometry & Chemical Biology Laboratory, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022, PR China.
Liu ZQ; National Center of Mass Spectrometry in Changchun & Jilin Province Key Laboratory of Chinese Medicine Chemistry and Mass Spectrometry & Chemical Biology Laboratory, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022, PR China. Electronic address: liuzq@c

J Pharm Biomed Anal ; 148: 298-306, 2018 Jan 30.

Article em En | MEDLINE | ID: mdl-29078174

Assuntos

Bactérias/efeitos dos fármacos; Medicamentos de Ervas Chinesas/química; Medicamentos de Ervas Chinesas/farmacologia; Microbioma Gastrointestinal/efeitos dos fármacos; Polygala/química; Cromatografia Líquida de Alta Pressão/métodos; Glicosídeos/química; Intestinos/microbiologia; Medicina Tradicional Chinesa/métodos; Metaboloma/efeitos dos fármacos; Oligossacarídeos/química; Raízes de Plantas/química; Saponinas/química; Saponinas/farmacologia; Espectrometria de Massas em Tandem/métodos; Xantonas/química

Palavras-chave

Intestinal microflora; Metabolic profile; Polygalae radix; UHPLC-IT-MS(n); UHPLC-Q-TOF-MS

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bactérias / Medicamentos de Ervas Chinesas / Polygala / Microbioma Gastrointestinal Tipo de estudo: Diagnostic_studies Idioma: En Revista: J Pharm Biomed Anal Ano de publicação: 2018 Tipo de documento: Article

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