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Specific Inhibition of Bacterial ß-Glucuronidase by Pyrazolo[4,3-c]quinoline Derivatives via a pH-Dependent Manner To Suppress Chemotherapy-Induced Intestinal Toxicity.
Cheng, Kai-Wen; Tseng, Chih-Hua; Yang, Chia-Ning; Tzeng, Cherng-Chyi; Cheng, Ta-Chun; Leu, Yu-Lin; Chuang, Yu-Chung; Wang, Jaw-Yuan; Lu, Yun-Chi; Chen, Yeh-Long; Cheng, Tian-Lu.
Afiliação
  • Cheng KW; Institute of Biomedical Sciences, National Sun Yat-sen University , Kaohsiung 804, Taiwan.
  • Tseng CH; School of Pharmacy, Kaohsiung Medical University , Kaohsiung 807, Taiwan.
  • Yang CN; Department of Fragrance and Cosmetic Science, Kaohsiung Medical University , Kaohsiung 807, Taiwan.
  • Tzeng CC; Research Center for Natural Products and Drug Development, Kaohsiung Medical University , Kaohsiung 807, Taiwan.
  • Cheng TC; Center for Infectious Disease and Cancer Research, Kaohsiung Medical University , Kaohsiung 807, Taiwan.
  • Leu YL; Department of Life Sciences, National University of Kaohsiung , Kaohsiung 811, Taiwan.
  • Chuang YC; Research Center for Natural Products and Drug Development, Kaohsiung Medical University , Kaohsiung 807, Taiwan.
  • Wang JY; Department of Medicinal and Applied Chemistry, Kaohsiung Medical University , Kaohsiung 807, Taiwan.
  • Lu YC; Center for Biomarkers and Biotech Drugs, Kaohsiung Medical University , Kaohsiung 807, Taiwan.
  • Chen YL; Department of Pharmacy, Chia Nan University of Pharmacy and Science , Tainan City 717, Tainan.
  • Cheng TL; Department of Life Sciences, National University of Kaohsiung , Kaohsiung 811, Taiwan.
J Med Chem ; 60(22): 9222-9238, 2017 11 22.
Article em En | MEDLINE | ID: mdl-29120626
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirazóis / Quinolinas / Substâncias Protetoras / Glucuronidase / Intestinos Limite: Animals / Humans Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Taiwan
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirazóis / Quinolinas / Substâncias Protetoras / Glucuronidase / Intestinos Limite: Animals / Humans Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Taiwan