Congenital Hypothyroidism in Neonates of a Tertiary Care Hospital.
Pak J Med Sci
; 33(5): 1269-1272, 2017.
Article
em En
| MEDLINE
| ID: mdl-29142577
ABSTRACT
OBJECTIVE:
To determine neonatal congenital hypothyroidism among neonates born in a tertiary care hospital of Lahore Pakistan.METHODS:
This cross-sectional study was carried out at Pathology Department of Allama Iqbal Medical College, Lahore in collaboration with Pediatrics and Gynecology & Obstetrics Department, Jinnah Hospital, Lahore Pakistan. A total of 770 babies were included in this study, both male and female. About 2 ml venous blood samples were collected aseptically from the neonates in sterile clotted tube. Serum was separated and serum TSH was determined by ELISA method.RESULTS:
Out of total 770 neonates, 48.9% were female and 51.0% were males with the ratio of 11.04. Neonatal congenital hypothyroidisim (TSH, >30 mIU/L), was observed in 0.4% (Frequency, 1257) nenates, with the incidence rate of 1257. Female to male ratio of hypothyroid neonates was 21. The mode of delivery vise distribution showed, among n=251 neonates born by normal delivery, only a single case of hypothyroidism was detected, and among n=519 neonates delivered by cesarean section, only two neonates were belong to hypothyroidism.CONCLUSION:
The frequency of Congenital Hypothyroidism is notably higher in pediatric community than reported in most other countries. This result emphasizes the necessity of a nationwide screening program.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Tipo de estudo:
Observational_studies
/
Risk_factors_studies
Idioma:
En
Revista:
Pak J Med Sci
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Paquistão