C-peptide prevents NF-&#954;B from recruiting p300 and binding to the inos promoter in diabetic nephropathy.

Li, Yanning; Li, Xiaoping; He, Kunyu; Li, Bin; Liu, Kun; Qi, Jinsheng; Wang, Hui; Wang, Yu; Luo, Weigang

C-peptide prevents NF-κB from recruiting p300 and binding to the inos promoter in diabetic nephropathy.

Li, Yanning; Li, Xiaoping; He, Kunyu; Li, Bin; Liu, Kun; Qi, Jinsheng; Wang, Hui; Wang, Yu; Luo, Weigang.

Afiliação

Li Y; Department of Biochemistry, Hebei Key Laboratory of Medical Biotechnology, Hebei Medical University, Shijiazhuang, China.
Li X; Department of Molecular Biology, Hebei Key Laboratory of Laboratory Animals, Hebei Medical University, Shijiazhuang, China.
He K; Department of Molecular Biology, Hebei Key Laboratory of Laboratory Animals, Hebei Medical University, Shijiazhuang, China.
Li B; Department of Molecular Biology, Hebei Key Laboratory of Laboratory Animals, Hebei Medical University, Shijiazhuang, China.
Liu K; Department of Molecular Biology, Hebei Key Laboratory of Laboratory Animals, Hebei Medical University, Shijiazhuang, China.
Qi J; Department of Molecular Biology, Hebei Key Laboratory of Laboratory Animals, Hebei Medical University, Shijiazhuang, China.
Wang H; Department of Pathology, Hebei Medical University, Shijiazhuang, China.
Wang Y; Department of Biochemistry, Hebei Key Laboratory of Medical Biotechnology, Hebei Medical University, Shijiazhuang, China.
Luo W; Department of Biochemistry, Hebei Key Laboratory of Medical Biotechnology, Hebei Medical University, Shijiazhuang, China.

FASEB J ; 32(4): 2269-2279, 2018 04.

Article em En | MEDLINE | ID: mdl-29229684

Assuntos

Peptídeo C/metabolismo; Nefropatias Diabéticas/metabolismo; NF-kappa B/metabolismo; Óxido Nítrico Sintase Tipo II/genética; Regiões Promotoras Genéticas; Fatores de Transcrição de p300-CBP/metabolismo; Acetilação; Animais; Células Cultivadas; Histonas/metabolismo; Masculino; Células Mesangiais/metabolismo; Óxido Nítrico Sintase Tipo II/metabolismo; Ligação Proteica; Processamento de Proteína Pós-Traducional; Ratos; Ratos Sprague-Dawley

Palavras-chave

high glucose; oxidative stress; peptide; transcriptional regulation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeo C / NF-kappa B / Regiões Promotoras Genéticas / Nefropatias Diabéticas / Óxido Nítrico Sintase Tipo II / Fatores de Transcrição de p300-CBP Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: FASEB J Assunto da revista: BIOLOGIA / FISIOLOGIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: China

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