Oxaliplatin-induced acute tubulointerstitial nephritis: Two case reportsâ©.
Clin Nephrol
; 89(2): 130-134, 2018 Feb.
Article
em En
| MEDLINE
| ID: mdl-29231160
ABSTRACT
Oxaliplatin is a platinum compound commonly used in the treatment of advanced colorectal cancer. This report describes two patients who had received repetitive combination chemotherapy including oxaliplatin for the treatment of metastatic colon cancer and who visited the emergency department with acute kidney injury several days after experiencing a hypersensitivity reaction to oxaliplatin. In both cases, the pathologic diagnosis was acute tubulointerstitial nephritis, and corticosteroid therapy resulted in improved renal function. Induction of acute tubulointerstitial nephritis by oxaliplatin has rarely been reported.â©.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Compostos Organoplatínicos
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Neoplasias do Colo
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Hipersensibilidade a Drogas
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Injúria Renal Aguda
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Nefrite Intersticial
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Antineoplásicos
Limite:
Humans
/
Male
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Middle aged
Idioma:
En
Revista:
Clin Nephrol
Ano de publicação:
2018
Tipo de documento:
Article