Syndecan-1 as a biomarker for sepsis survival after major abdominal surgery.
Biomark Med
; 12(2): 119-127, 2018 02.
Article
em En
| MEDLINE
| ID: mdl-29327601
ABSTRACT
AIM:
Sepsis is a serious complication following surgery and identification of patients at risk is of high importance. Syndecan-1 (sSDC1) levels are known to be elevated during sepsis. MATERIALS &METHODS:
Fifty-five patients scheduled for major abdominal surgery were prospectively included and sSDC1 concentrations were measured during hospital stay.RESULTS:
Patients with postoperative sepsis showed a continued increase of sSDC1 levels and exhibited higher median sSDC1 concentrations at day 1 compared with nonseptic patients 90.3 versus 16.5 ng/ml. A significant association of sSDC1 levels with the incidence of sepsis and death was demonstrated.CONCLUSION:
This study identifies sSDC1 as potential biomarker for sepsis and survival after abdominal surgery.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Biomarcadores
/
Sepse
/
Abdome
/
Sindecana-1
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Biomark Med
Assunto da revista:
BIOQUIMICA
/
MEDICINA
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
Alemanha