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A small-molecule inhibitor of the ubiquitin activating enzyme for cancer treatment.
Hyer, Marc L; Milhollen, Michael A; Ciavarri, Jeff; Fleming, Paul; Traore, Tary; Sappal, Darshan; Huck, Jessica; Shi, Judy; Gavin, James; Brownell, Jim; Yang, Yu; Stringer, Bradley; Griffin, Robert; Bruzzese, Frank; Soucy, Teresa; Duffy, Jennifer; Rabino, Claudia; Riceberg, Jessica; Hoar, Kara; Lublinsky, Anya; Menon, Saurabh; Sintchak, Michael; Bump, Nancy; Pulukuri, Sai M; Langston, Steve; Tirrell, Stephen; Kuranda, Mike; Veiby, Petter; Newcomb, John; Li, Ping; Wu, Jing Tao; Powe, Josh; Dick, Lawrence R; Greenspan, Paul; Galvin, Katherine; Manfredi, Mark; Claiborne, Chris; Amidon, Benjamin S; Bence, Neil F.
Afiliação
  • Hyer ML; Takeda Pharmaceuticals Inc., Cambridge, Massachusetts, USA.
  • Milhollen MA; Takeda Pharmaceuticals Inc., Cambridge, Massachusetts, USA.
  • Ciavarri J; Takeda Pharmaceuticals Inc., Cambridge, Massachusetts, USA.
  • Fleming P; Takeda Pharmaceuticals Inc., Cambridge, Massachusetts, USA.
  • Traore T; Takeda Pharmaceuticals Inc., Cambridge, Massachusetts, USA.
  • Sappal D; Takeda Pharmaceuticals Inc., Cambridge, Massachusetts, USA.
  • Huck J; Takeda Pharmaceuticals Inc., Cambridge, Massachusetts, USA.
  • Shi J; Takeda Pharmaceuticals Inc., Cambridge, Massachusetts, USA.
  • Gavin J; Takeda Pharmaceuticals Inc., Cambridge, Massachusetts, USA.
  • Brownell J; Takeda Pharmaceuticals Inc., Cambridge, Massachusetts, USA.
  • Yang Y; Takeda Pharmaceuticals Inc., Cambridge, Massachusetts, USA.
  • Stringer B; Takeda Pharmaceuticals Inc., Cambridge, Massachusetts, USA.
  • Griffin R; Takeda Pharmaceuticals Inc., Cambridge, Massachusetts, USA.
  • Bruzzese F; Takeda Pharmaceuticals Inc., Cambridge, Massachusetts, USA.
  • Soucy T; Takeda Pharmaceuticals Inc., Cambridge, Massachusetts, USA.
  • Duffy J; Takeda Pharmaceuticals Inc., Cambridge, Massachusetts, USA.
  • Rabino C; Takeda Pharmaceuticals Inc., Cambridge, Massachusetts, USA.
  • Riceberg J; Takeda Pharmaceuticals Inc., Cambridge, Massachusetts, USA.
  • Hoar K; Takeda Pharmaceuticals Inc., Cambridge, Massachusetts, USA.
  • Lublinsky A; Takeda Pharmaceuticals Inc., Cambridge, Massachusetts, USA.
  • Menon S; Takeda Pharmaceuticals Inc., Cambridge, Massachusetts, USA.
  • Sintchak M; Takeda Pharmaceuticals Inc., Cambridge, Massachusetts, USA.
  • Bump N; Takeda Pharmaceuticals Inc., Cambridge, Massachusetts, USA.
  • Pulukuri SM; Takeda Pharmaceuticals Inc., Cambridge, Massachusetts, USA.
  • Langston S; Takeda Pharmaceuticals Inc., Cambridge, Massachusetts, USA.
  • Tirrell S; Takeda Pharmaceuticals Inc., Cambridge, Massachusetts, USA.
  • Kuranda M; Takeda Pharmaceuticals Inc., Cambridge, Massachusetts, USA.
  • Veiby P; Takeda Pharmaceuticals Inc., Cambridge, Massachusetts, USA.
  • Newcomb J; Takeda Pharmaceuticals Inc., Cambridge, Massachusetts, USA.
  • Li P; Takeda Pharmaceuticals Inc., Cambridge, Massachusetts, USA.
  • Wu JT; Takeda Pharmaceuticals Inc., Cambridge, Massachusetts, USA.
  • Powe J; Takeda Pharmaceuticals Inc., Cambridge, Massachusetts, USA.
  • Dick LR; Takeda Pharmaceuticals Inc., Cambridge, Massachusetts, USA.
  • Greenspan P; Takeda Pharmaceuticals Inc., Cambridge, Massachusetts, USA.
  • Galvin K; Takeda Pharmaceuticals Inc., Cambridge, Massachusetts, USA.
  • Manfredi M; Takeda Pharmaceuticals Inc., Cambridge, Massachusetts, USA.
  • Claiborne C; Takeda Pharmaceuticals Inc., Cambridge, Massachusetts, USA.
  • Amidon BS; Takeda Pharmaceuticals Inc., Cambridge, Massachusetts, USA.
  • Bence NF; Takeda Pharmaceuticals Inc., Cambridge, Massachusetts, USA.
Nat Med ; 24(2): 186-193, 2018 02.
Article em En | MEDLINE | ID: mdl-29334375
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sulfonamidas / Enzimas Ativadoras de Ubiquitina / Bibliotecas de Moléculas Pequenas / Neoplasias / Nucleosídeos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Nat Med Assunto da revista: BIOLOGIA MOLECULAR / MEDICINA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sulfonamidas / Enzimas Ativadoras de Ubiquitina / Bibliotecas de Moléculas Pequenas / Neoplasias / Nucleosídeos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Nat Med Assunto da revista: BIOLOGIA MOLECULAR / MEDICINA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos