Suppressor T cells in myasthenia gravis and antibodies to acetylcholine receptor.
Ann Neurol
; 19(1): 87-9, 1986 Jan.
Article
em En
| MEDLINE
| ID: mdl-2936299
ABSTRACT
We cultured blood mononuclear cells of patients with myasthenia gravis both with and without removal of T8 suppressor cells. The levels of synthesized antibodies to acetylcholine receptor and IgG as well as the frequency of immunoglobulin-secreting cells were all higher in pokeweed mitogen-stimulated cultures depleted of T8+ cells. Thus, autologous suppressor cells within the T8+ population exert some regulatory control over antiacetylcholine receptor-producing cells in patients with myasthenia gravis.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Receptores Colinérgicos
/
Linfócitos T Reguladores
/
Anticorpos
/
Miastenia Gravis
Limite:
Adult
/
Humans
/
Middle aged
Idioma:
En
Revista:
Ann Neurol
Ano de publicação:
1986
Tipo de documento:
Article