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Striatal neurons directly converted from Huntington's disease patient fibroblasts recapitulate age-associated disease phenotypes.
Victor, Matheus B; Richner, Michelle; Olsen, Hannah E; Lee, Seong Won; Monteys, Alejandro M; Ma, Chunyu; Huh, Christine J; Zhang, Bo; Davidson, Beverly L; Yang, X William; Yoo, Andrew S.
Afiliação
  • Victor MB; Department of Developmental Biology, Center for Regenerative Medicine, Washington University School of Medicine, St. Louis, MO, USA.
  • Richner M; Graduate Program in Neuroscience, Division of Biology and Biomedical Sciences, Washington University School of Medicine, St. Louis, MO, USA.
  • Olsen HE; Department of Developmental Biology, Center for Regenerative Medicine, Washington University School of Medicine, St. Louis, MO, USA.
  • Lee SW; Department of Developmental Biology, Center for Regenerative Medicine, Washington University School of Medicine, St. Louis, MO, USA.
  • Monteys AM; Department of Developmental Biology, Center for Regenerative Medicine, Washington University School of Medicine, St. Louis, MO, USA.
  • Ma C; The Raymond G Perelman Center for Cellular and Molecular Therapeutics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Huh CJ; Department of Developmental Biology, Center for Regenerative Medicine, Washington University School of Medicine, St. Louis, MO, USA.
  • Zhang B; Department of Developmental Biology, Center for Regenerative Medicine, Washington University School of Medicine, St. Louis, MO, USA.
  • Davidson BL; Department of Developmental Biology, Center for Regenerative Medicine, Washington University School of Medicine, St. Louis, MO, USA.
  • Yang XW; The Raymond G Perelman Center for Cellular and Molecular Therapeutics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Yoo AS; Department of Pathology & Laboratory Medicine, The University of Pennsylvania, Philadelphia, PA, USA.
Nat Neurosci ; 21(3): 341-352, 2018 03.
Article em En | MEDLINE | ID: mdl-29403030
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Envelhecimento / Neostriado / Doença de Huntington / Fibroblastos / Neurônios Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Revista: Nat Neurosci Assunto da revista: NEUROLOGIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Envelhecimento / Neostriado / Doença de Huntington / Fibroblastos / Neurônios Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Revista: Nat Neurosci Assunto da revista: NEUROLOGIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos