Eosinophilic oesophagitis: Current evidence-based diagnosis and treatment. / Esofagitis eosinofílica: diagnóstico y tratamiento actual basado en la evidencia.
Gastroenterol Hepatol
; 41(4): 281-291, 2018 Apr.
Article
em En, Es
| MEDLINE
| ID: mdl-29422238
ABSTRACT
Eosinophilic oesophagitis (EoE) is a disease caused by an immune response to food antigens in contact with the oesophageal mucosa. Its diagnosis is defined by the combination of oesophageal dysfunction symptoms and inflammation of the oesophageal mucosa predominantly by eosinophils. Its chronic course and frequent progression to subepithelial fibrosis and oesophageal strictures indicate the need for treatment. The information provided by recent clinical trials and systematic reviews has led to the development of new clinical guidelines, endorsed by several European scientific societies. This review includes the most relevant aspects of the new guidelines, updates the EoE concept and reports its epidemiology and risk factors, associated conditions and its natural history in children and adults. Diagnostic criteria are provided, and tests for EoE diagnosis and monitoring and therapeutic options are analysed based on the best scientific evidence and consensus opinion of experts.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Esofagite Eosinofílica
Tipo de estudo:
Diagnostic_studies
/
Guideline
/
Risk_factors_studies
Limite:
Humans
Idioma:
En
/
Es
Revista:
Gastroenterol Hepatol
Ano de publicação:
2018
Tipo de documento:
Article