Circadian clock-dependent and -independent posttranscriptional regulation underlies temporal mRNA accumulation in mouse liver.

Wang, Jingkui; Symul, Laura; Yeung, Jake; Gobet, Cédric; Sobel, Jonathan; Lück, Sarah; Westermark, Pål O; Molina, Nacho; Naef, Felix

Wang, Jingkui; Symul, Laura; Yeung, Jake; Gobet, Cédric; Sobel, Jonathan; Lück, Sarah; Westermark, Pål O; Molina, Nacho; Naef, Felix.

Afiliação

Wang J; Institute of Bioengineering, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland.
Symul L; Institute of Bioengineering, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland.
Yeung J; Institute of Bioengineering, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland.
Gobet C; Institute of Bioengineering, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland.
Sobel J; Nestlé Institute of Health Sciences, CH-1015 Lausanne, Switzerland.
Lück S; Institute of Bioengineering, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland.
Westermark PO; Institute for Theoretical Biology, Charité-Universitätsmedizin Berlin, D-10115 Berlin, Germany.
Molina N; Institute of Genetics and Biometry, Leibniz Institute for Farm Animal Biology, D-18196 Dummerstorf, Germany.
Naef F; Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS, INSERM, University of Strasbourg, 67404 Illkirch, France.

Proc Natl Acad Sci U S A ; 115(8): E1916-E1925, 2018 02 20.

Article em En | MEDLINE | ID: mdl-29432155

Assuntos

Relógios Circadianos; Regulação da Expressão Gênica; Fígado/metabolismo; Camundongos/genética; RNA Mensageiro/genética; Animais; Masculino; Camundongos/metabolismo; Camundongos Endogâmicos C57BL; Regiões Promotoras Genéticas; RNA Mensageiro/metabolismo; Transcrição Gênica

Palavras-chave

RNA binding proteins; circadian clock; mRNA half-lives; posttranscriptional regulation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: RNA Mensageiro / Regulação da Expressão Gênica / Relógios Circadianos / Fígado / Camundongos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Suíça

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