Long-term diet-induced hypertension in rats is associated with reduced expression and function of small artery SK<sub>Ca</sub>, IK<sub>Ca</sub>, and Kir2.1 channels.

Gradel, Anna K J; Salomonsson, Max; Sørensen, Charlotte M; Holstein-Rathlou, Niels-Henrik; Jensen, Lars Jørn

Long-term diet-induced hypertension in rats is associated with reduced expression and function of small artery SK_Ca, IK_Ca, and Kir2.1 channels.

Gradel, Anna K J; Salomonsson, Max; Sørensen, Charlotte M; Holstein-Rathlou, Niels-Henrik; Jensen, Lars Jørn.

Afiliação

Gradel AKJ; Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Salomonsson M; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Sørensen CM; Medical Ward 12, Trelleborg Hospital, Trelleborg, Sweden.
Holstein-Rathlou NH; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Jensen LJ; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

Clin Sci (Lond) ; 132(4): 461-474, 2018 02 28.

Article em En | MEDLINE | ID: mdl-29436481

Assuntos

Acetilcolina/farmacologia; Dieta; Hipertensão/etiologia; Canais de Potássio Ativados por Cálcio de Condutância Intermediária/metabolismo; Canais de Potássio Corretores do Fluxo de Internalização/metabolismo; Animais; Cálcio/metabolismo; Endotélio Vascular/metabolismo; Masculino; Ratos Sprague-Dawley; Tempo

Palavras-chave

diet-induced obesity; hypertension; potassium channels; small arteries; vascular tone

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Acetilcolina / Canais de Potássio Corretores do Fluxo de Internalização / Dieta / Canais de Potássio Ativados por Cálcio de Condutância Intermediária / Hipertensão Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals Idioma: En Revista: Clin Sci (Lond) Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Dinamarca

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