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Molecular characterization of ERBB2-amplified colorectal cancer identifies potential mechanisms of resistance to targeted therapies: a report of two instructive cases.
Owen, Daniel R; Wong, Hui-Li; Bonakdar, Melika; Jones, Martin; Hughes, Christopher S; Morin, Gregg B; Jones, Steven J M; Renouf, Daniel J; Lim, Howard; Laskin, Janessa; Marra, Marco; Yip, Stephen; Schaeffer, David F.
Afiliação
  • Owen DR; Department of Pathology and Laboratory Medicine, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia V6T 2B5, Canada.
  • Wong HL; Department of Pathology & Laboratory Medicine, Vancouver General Hospital, Vancouver, British Columbia V5Z 1M9, Canada.
  • Bonakdar M; Division of Medical Oncology, British Columbia Cancer Agency, Vancouver, British Columbia V5Z 4E63, Canada.
  • Jones M; Canada's Michael Smith Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, British Columbia V5Z 4S6, Canada.
  • Hughes CS; Canada's Michael Smith Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, British Columbia V5Z 4S6, Canada.
  • Morin GB; Canada's Michael Smith Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, British Columbia V5Z 4S6, Canada.
  • Jones SJM; Canada's Michael Smith Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, British Columbia V5Z 4S6, Canada.
  • Renouf DJ; Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia V6H 3N1, Canada.
  • Lim H; Canada's Michael Smith Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, British Columbia V5Z 4S6, Canada.
  • Laskin J; Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia V6H 3N1, Canada.
  • Marra M; Division of Medical Oncology, British Columbia Cancer Agency, Vancouver, British Columbia V5Z 4E63, Canada.
  • Yip S; Division of Medical Oncology, British Columbia Cancer Agency, Vancouver, British Columbia V5Z 4E63, Canada.
  • Schaeffer DF; Canada's Michael Smith Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, British Columbia V5Z 4S6, Canada.
Cold Spring Harb Mol Case Stud ; 4(2)2018 04.
Article em En | MEDLINE | ID: mdl-29438965
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Biomarcadores Tumorais / Amplificação de Genes / Receptor ErbB-2 / Resistencia a Medicamentos Antineoplásicos Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Female / Humans / Male / Middle aged Idioma: En Revista: Cold Spring Harb Mol Case Stud Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Canadá
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Biomarcadores Tumorais / Amplificação de Genes / Receptor ErbB-2 / Resistencia a Medicamentos Antineoplásicos Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Female / Humans / Male / Middle aged Idioma: En Revista: Cold Spring Harb Mol Case Stud Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Canadá